Developing appropriate risk reduction interventions for pre-teens

描述（由申请人提供）：超过一半的新艾滋病毒感染者发生在24岁以下的年轻人中。在撒哈拉以南非洲，年轻妇女承受着艾滋病毒疾病的负担。在南非，尽管人们对艾滋病毒/艾滋病的认识很高，但目前的艾滋病毒预防项目并没有对行为改变产生影响。这可能是由于从种族隔离过渡以来社会发生了显著变化，伴随着城市化的迅速发展、家庭结构的解体、对青少年性行为、当前青年的态度和做法以及不具体情况的预防信息普遍缺乏了解。需要制定战略，在青春期前和青少年中成功地检测艾滋病毒预防疫苗。目前，有两种很有希望的艾滋病毒候选疫苗正在IIb期或概念验证试验中进行测试，青少年即将参与其中一项试验。本探索性研究的目的是为青少年前和青少年艾滋病毒疫苗试验参与者开发和验证一种适合文化和年龄的降低风险咨询干预措施。需要制定战略，在青春期前和青少年中成功地检测艾滋病毒预防疫苗。目前，有两种很有希望的艾滋病毒候选疫苗正在IIb期或“概念测试”试验中进行测试，青少年即将参与其中一项试验。本探索性研究的目的是为青少年前和青少年艾滋病毒疫苗试验参与者开发和验证一种文化上和发展上适当的降低风险咨询干预措施。

DESCRIPTION (provided by applicant): More than half of all new HIV infections occur in young people below the age of 24 years. In sub-Saharan Africa, young women bear the burden of HIV disease. In South Africa, current HIV prevention programs have not impacted on behavior change despite high levels of HIV/AIDS awareness. This may be attributed to the marked changes in society seen since the transition from apartheid with concomitant rapid rates of urbanization, disintegration of family structures, and a general lack of understanding of adolescent sexuality, current youth attitudes and practices, as well as prevention messages that are not context specific. Strategies are required to successfully test HIV preventative vaccines in pre-teens and adolescents. Currently, there are two promising HIV vaccine candidates that are being tested in phase IIb or proof of concept trials, and adolescent involvement in one of these trials is imminent. The purpose of this exploratory research is to develop and validate a cultural- and age-appropriate risk reduction counseling intervention for pre-teens and adolescent HIV vaccine trial participants. Strategies are required to successfully test HIV preventative vaccines in pre-teens and adolescents. Currently, there are two promising HIV vaccine candidates that are being tested in phase IIb or "test of concept" trials, and adolescent involvement in one of these trials is imminent. The purpose of this exploratory research is to develop and validate a culturally and developmentally appropriate risk reduction counseling intervention for pre-teens and adolescent HIV vaccine trial participants.