Research in Perinatal Medicine

描述(由申请人提供)：项目摘要：这个博士后项目的目标是为新生儿科医生和其他对发育医学感兴趣的人提供成功的学术生涯所必需的技能。尽管美国有许多新生儿-围产期医学的临床培训项目，但很少有项目提供发育生物学方面的强化实验室经验，或者提供临床研究和流行病学方面的系统培训。耶鲁大学的临床和基础科学系都参与了这个项目，包括儿科、内科、遗传学、病理学、细胞和分子生理学、神经生物学、免疫生物学和流行病学。这些部门的广泛资源可供学员使用，耶鲁-纽黑文儿童医院的新生儿特别护理单位的设施也是如此，这是一个有51个床位的三级护理单位。对于选择以实验室为基础的密集研究经验的受训者，可提供细胞生物学、分子生物学和遗传学的结构化课程作业。选择从事临床研究的学员参加临床试验设计、统计学和流行病学的课程。他们也可能成为耶鲁大学公共卫生学院公共卫生硕士学位或调查医学博士的候选人。该项目支持4名博士后实习生。实习生的任期为3年，必须致力于学术医学的职业生涯。MD实习生将在进入该计划之前完成他们的实习。博士毕业生将对发育生物学表现出浓厚的兴趣。经过一段时间的培训后，学员会选择一位导师和一个研究项目。在导师的直接监督下，他们设计、执行、解释和报告他们的研究。由于3年的时间通常不足以建立独立的研究生涯，因此鼓励和帮助学员申请资金以延长他们的研究培训，许多人已经成功地这样做了。这个项目已经运作了28年，毕业生在全美各地担任学术职位。许多人已经成为围产期医学和研究的领导者。相关性：内科医生-科学家为生物医学研究及其翻译带来了独特的视角。人们已经认识到，全国缺乏训练有素的内科科学家。该计划的持续目标是培训下一代围产期研究人员。

DESCRIPTION (provided by applicant): Project Summary: The goal of this postdoctoral program, since its inception in 1977, has been to provide neonatologists and others interested in developmental medicine with the skills necessary for a successful academic career. Although there are many clinical training programs in neonatal-perinatal medicine in the United States, few offer either an intensive laboratory experience in developmental biology, or structured training in clinical research and epidemiology. Both clinical and basic science departments at Yale University are involved with the program including Pediatrics, Internal Medicine, Genetics, Pathology, Cellular and Molecular Physiology, Neurobiology, Immunobiology and Epidemiology. The extensive resources of these departments are available to trainees as are the facilities of the Newborn Special Care Unit, a 51 bed tertiary care unit in the Yale-New Haven Children's Hospital. For the trainees who choose an intensive laboratory based research experience, structured course work is available in cell biology, molecular biology and genetics. Trainees who elect to do clinical research attend courses in design of clinical trials, statistics and epidemiology. They may also become candidates for the MPH degree at the Yale School of Public Health or the PhD in Investigative Medicine. This program supports 4 postdoctoral trainees. Trainees are appointed for 3 years and must be committed to pursuing a career in academic medicine. MD trainees will have completed their residency prior to entering the program. PhD graduates will have a demonstrated interest in developmental biology. After an orientation period, trainees select a preceptor and a research project. Under the direct supervision of the preceptor, they design, execute, interpret and report their research. Since 3 years are generally insufficient to establish an independent research career, trainees are encouraged and assisted to apply for funding to extend their research training, and many have done so successfully. Graduates of this program, which has now been functioning for over 28 years, hold academic positions throughout the United States. Many have become leaders in perinatal medicine and research. Relevance: Physician-scientists bring a unique perspective to biomedical research and its translation. It has been recognized that there is a national shortage of suitably trained physician-scientists. The ongoing objective of this program is to train members of the next generation of perinatal investigators.