Training Program in Basic and Clinical Communication Science

描述（由申请人提供）：这是一份修订后的A2培训计划申请，旨在为基础和临床科学相结合的医学生，耳鼻喉科住院医师，研究生和博士后学员寻求资金支持，该计划针对与沟通障碍相关的科学。该培训计划的目标是培养一种新型的临床科学家，他们随时准备交流思想，专业知识和技术，从而将基础科学发现直接有效地转化为临床测试和应用。此外，这样的临床科学家将有能力产生来自临床研究的机制假设，这些假设可以直接在基本细胞水平上进行测试。第二个目标是培养新的博士和博士后科学家，他们不仅能够建立独立的研究计划，而且善于识别相关的基础科学问题并将其整合为临床相关的答案和解决方案。这将通过吸收基本的博士前和博士后研究员，到一个“学说”的培训计划。培训计划将在耳鼻喉科传播科学方案的主持下运作，该方案吸引了来自5所学校和12个部门的43名教师（28名小学生和15名准成员），使其成为一个多学科方案。培训师有校外资助的研究项目，包括行为，系统，细胞/分子生物学，生物化学，生理学和使用动物模型的转化研究（例如，C. elegans，primates）and humans人类.这些培训师的主要研究重点是感官和沟通科学和疾病。拟议的培训方案将通过正式的课程工作得到加强，这些课程工作将侧重于：1）传播科学，2）暑期学校，3）从板凳到床边的“学说”，4）生物统计学和流行病学，包括临床研究设计，5）生物伦理学，6）分子生物学和遗传学，重点是人类遗传学和疾病，7）口头陈述技能，8）赠款和手稿写作策略，（9）了解与职业相关的问题。此外，培训计划将赞助年度务虚会和杰出演讲者研讨会。要求为2.5名受训人员提供资金。该机构的承诺将涵盖1.5名学员，以确保每年由4名学员组成的基础和临床转化科学计划的平衡。

DESCRIPTION (provided by applicant): This is a revised - A2 - application for a training program to seek funding support for medical students, ENT residents, graduate and postdoctoral trainees in a blend of basic and clinical science, which is tailored towards the science related to communicative disorders. The goal of this training program is to produce a new type of clinician scientist who is poised to exchange ideas, expertise, and techniques leading to the direct and effective flow and translation of basic-science discoveries into clinical testing and applications. In addition, such a clinical scientist will have the ability to generate mechanistic hypotheses that are derived from clinical research, which can be tested directly at the basic cellular level. The second objective is to produce new PhDs and postdoctoral scientists, who are not only capable of establishing independent research programs, but are also adept at recognizing and integrating relevant basic-science problems into clinically germane answers and solutions. This will be done by assimilating basic pre- and postdoctoral fellows, into a "doctrine" training program. The training plan will operate under the auspices of the Communication Science Program in the Department of Otolaryngology, which draws 43 faculty (28 primary and 15 associate members) from 5 schools and 12 departments making it a multidisciplinary program. The trainers have extramurally funded research programs that incorporate approaches ranging from behavior, systems, cellular/molecular biology, biochemistry, physiology and translational research using animal models (e.g., C. elegans, primates) and humans. The primary research emphasis of these trainers is on sensory and communication sciences and disorders. The proposed training program will be enhanced with formal course work that will focus on: 1) communication science, 2) summer schools, 3) "doctrine" from bench to bedside, 4) biostatistics and epidemiology including clinical-study design, 5) bioethics, 6) molecular biology and genetics, with emphasis on human genetics and diseases, 7) oral presentations skills, 8) grant and manuscript writing strategies, and 9) understanding career-related issues. In addition, the training program will sponsor an annual retreat and Distinguished Speaker Seminars. Funds for 2.5 trainees are requested. The institution commitment will cover 1.5 trainees to ensure a balance of a basic and clinical translational science program consisting of 4 trainees per year.