Training in Pediatric Endocrinology and Diabetes Research

描述(由申请人提供)： 这项提案寻求继续支持耶鲁大学儿科内分泌学/糖尿病研究项目的培训。该申请寻求增加目前的资助水平(从每年2到3个博士后津贴)。申请是基于我们培训计划和导师的记录；将该计划扩展到包括内分泌研究的所有领域；我们的临床、基础和转化性研究计划的质量和多样性；我们的一些受训人员获得博士学位所需的更长的培训期限，以及儿科内分泌学和糖尿病研究领域持续严重的内科科学家短缺。耶鲁大学有一系列令人印象深刻的资源支持这项计划，包括DERC，耶鲁儿童健康研究中心，磁共振研究中心，JDRF低血糖研究中心，耶鲁大学肌肉骨骼疾病核心中心，X-连锁性低磷血症中心，人类和翻译免疫学的新项目，以及最近由CTSA支持的耶鲁临床研究中心，该中心改变了该机构为临床和翻译研究提供的支持。我们的许多培训人员(即坦博兰、卡彭特、里夫基、舍温、舒尔曼、赫罗德和罗斯曼)在所有这些资源中都扮演着重要的领导角色。项目主任和培训教师是备受尊敬和富有成效的调查人员，拥有广泛的同行审查赠款支持，以资助受训者的项目，他们在培训博士后研究员方面有着出色的记录。博士后学员可以在五个主要研究领域中进行选择，包括1)T1 DM技术和治疗，2)自身免疫和(T1 DM中的3-细胞保存，3)儿童肥胖和T2 DM，4)骨生物学和疾病，5)发育生物学。我们教育活动的核心是研究医学计划(IMP)，该计划沿着两条途径提供严格的必修课和选修课，即以患者为中心和以疾病为中心。成功完成课程作业和论文项目将允许受训者获得通过 医学部。IMP课程面向非博士生。的核心部分 我们的少数族裔招聘努力是我们与莫尔豪斯医学院儿科系的关系，该系为他们的学生和住院医生提供暑期奖学金。

DESCRIPTION (provided by applicant): This proposal seeks continued support for the Yale Training in Pediatric Endocrinology/Diabetes Research Program. The application seeks an increase in the current level of funding (from 2 to 3 post-doctoral stipends per year).The request is based on the track record of our training program and mentors; extension of the program to include all areas of endocrine research; the quality and diversity of our clinical, basic and translational research programs; the extended period of training that is required for some of our trainees to obtain a PhD degree and the continuing dire shortage of physician-scientists in pediatric endocrinology and diabetes research. Yale has an impressive array of resources that support this program, including the DERC, the Yale Child Health Research Center, the Magnetic Resonance Research Center, the JDRF Center for the Study of Hypoglycemia, the Yale Core Center for Muscular Skeletal Diseases, the Center for X-linked Hypophosphatemia, the new program in Human and Translational Immunology and, most recently, the CTSA-supported Yale Center for Clinical Investigation that has transformed the support provided for clinical and translational research at this institution. Many of our training faculty (i.e., Tamborlane, Carpenter, Rivkees, Sherwin, Shulman, Herold and Rothman) have major leadership roles in all of these resources. The Program Directors and training faculty are highly respected and productive investigators with extensive peer-reviewed grant support to fund trainees' projects and they have an outstanding track record in training post-doctoral fellows. Post-doctoral trainees can choose between five major areas of research training including 1) T1DM technology & therapeutics, 2) autoimmunity & (3-cell preservation in T1DM, 3) childhood obesity & T2DM, 4) bone biology & disease and 5) developmental biology. A centerpiece of our educational activities is the Investigative Medicine Program (IMP) that provides a rigorous curriculum of required and elective courses along two pathways, i.e. patient-oriented and disease-oriented. Successful completion of course work and thesis project will allow trainees to receive a Ph.D. that is awarded through the Department of Medicine. IMP courses are available for non Ph.D. candidates. The centerpiece of our minority recruitment efforts is our relationship with the Department of Pediatrics at Morehouse School of Medicine that offers summer fellowships to their students and residents.