ANIMAL RESOURCES CORE

由Mollie Bloomsmith博士领导的动物资源核心将确保所有被选中的动物 该计划项目符合计划项目调查员共同制定的入学标准。在……里面 此外，核心成员将在整个赠款期间监测主题的状况，以确保 他们的持续适当性。非人灵长类受试者将从YNPRC群体获得 它保存着宝贵的恒河猴和黑猩猩资源，适合 这项研究。将提供兽医护理，以促进受试者的健康并管理 包括在计划项目中的实验程序。环境的丰富、社会化和 动物训练计划将用于促进非人类灵长类动物的心理健康 这些研究中的主题，并促进对这一重要人群进行高质量的研究。 动物资源核心的具体目标是：(1)审查健康和实验记录 所有动物受试者在分配之前，以确定他们是否符合下面描述的选择标准，(2) 定期审查计划项目中所有猴子和黑猩猩的健康状况，执行 常规临床检查，包括血液分析和眼科检查，并确保 计划项目继续使用单个动物是合适的，(3)协调分配 猴子和黑猩猩到特定的研究项目，从而避免用户之间的调度冲突 在计划项目中，(4)促进所有猴子和黑猩猩的心理健康 通过提供环境丰富以最大限度地减少行为问题，协调 将研究对象与其研究用途社会化，并训练动物与实验合作 使用阳性强化技术的程序，(5)审查尸检结果和 病理检查，以确定是否存在未诊断的健康问题，其性质 将保证排除在数据分析之外，(6)确保及时、彻底和高效地访问所有 计划项目成员要求的兽医和动物历史记录，以及，(7)确保 为指定的实验程序提供充分的麻醉监督和恢复记录。

The Animal Resources Core, to be led by Mollie Bloomsmith, PhD, will ensure that all animals selected for the Program Project meet the entrance criteria developed jointly by the Program Project investigators. In addition, members of the Core will monitor the status of the subjects throughout the grant period to ensure their continued appropriateness. The nonhuman primate subjects will be obtained from the YNPRC colony which maintains a valuable resource of rhesus macaques and chimpanzees of appropriate age classes for this research. Veterinary care will be supplied to promote health of the subjects and to manage the experimental procedures included in the Program Project. Environmental enrichment, socialization, and animal training programs will be applied to promote the psychological well-being of the nonhuman primate subjects in these studies, and to facilitate the conduct of high quality research with this important population. The specific aims of the Animal Resources Core are to: (1) Review the health and experimental records of all animal subjects prior to assignment, to determine if they meet the selection criteria described below, (2) review the health status of all monkeys and chimpanzees in the Program Project on a regular basis, perform routine clinical examinations including blood analyses and ophthalmologic examinations, and insure that the continued use of individual animals by the Program Project is appropriate, (3) coordinate the assignment of monkeys and chimpanzees to specific research projects, so as to avoid scheduling conflicts between users in the Program Project, (4) promote the psychological well-being of all monkeys and chimpanzees in the Program Project by providing'environmental enrichment to minimize behavioral problems, coordinate the socialization of subjects with their research use, and train animals to cooperate with experimental procedures using positive reinforcement techniques, (5) review results of postmortem autopsies and pathological surveys to determine whether undiagnosed health problems were present, the nature of which would warrant exclusion from the data analyses, (6) ensure prompt, thorough, and efficient access to all veterinary and animal-history records required by members of the Program Project, and, (7) ensure adequate oversight of anesthesia and documentation of recovery for designated experimental procedures.