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中文摘要
翻译
儿科心血管医学面临着一个悖论,即在心血管(CV)形态发生和疾病的基本机制方面取得了前所未有的科学突破,同时将这些生物医学进步转化为临床护理所需的熟练人员迅速流失。要扭转这一趋势,需要协调一致地将候选人招募到充满活力和成功的研究环境中,在这种环境中,长期学术成功的可能性是合理的。这种环境的一个重要组成部分是一个结构化的研究教育环境,在这个环境中,受训者获得成功开发和实施研究以及成功沟通所需的技能和知识 研究结果向学术界报告。这项提议的临床研究技能开发核心将 为新近毕业的有学术倾向的医生提供系统的培训环境 受过培训并希望开始翻译研究事业的人。该计划包括与SCCOR应用程序中的四个项目相关的指导性研究,与临床研究方法和生物伦理学有关的结构化课程,以及参加正在进行的跨学科博士后培训研讨会。每个受训者将有75%的F.T.E.用于临床研究培训(50%的F.T.E.用于研究,25%的F.T.E.用于课程),其余时间用于临床工作。SCCOR研究范式为有才华的未来内科科学家提供了一个独特的机会,让他们参与与儿科心血管疾病相关的最先进的翻译研究,同时获得将这一经验应用于广泛的未来研究主题所需的技能。在培训计划结束时,我们 预期每个研究员将能够通过对其研究领域的全面了解、在同行审查的期刊上发表文章的记录、申请外部资助机构的同行审查支助以及从博士后研究员身份过渡到初级教员职位,在持续的、有指导的学术职业道路上证明,实现了培训核心目标的客观实现。
英文摘要
Pediatric cardiovascular medicine faces the paradox of unprecedented scientific breakthroughs related to the basic mechanisms of cardiovascular (CV) morphogenesis and diseases and a simultaneous rapid attrition of the skilled personnel required to translate these biomedical advances into clinical care. Reversing this trend requires the coordinated recruitment of candidates into dynamic and successful research environments where there is a reasonable likelihood for long-term academic success. One critical component of this environment is a structured research educational environment where trainees acquire the skills and knowledge to successfully develop and implement research as well as successfully communicate results to the academic community. This proposed Clinical Research Skills Development Core will provide a structured training environment for academically inclined physicians who are recently trained and who wish to embark upon a career in translational research. The program consists of mentored research related to the four projects within the SCCOR application, structured courses related to clinical research methods and bioethics, and participation in ongoing interdisciplinary post-doctoral training seminars. Each trainee will have 75% F.T.E. protected for clinical research training (50% F.T.E. for research and 25% F.T.E. for coursework) with the remaining time spent on clinical duties. The SCCOR research paradigm provides a unique opportunity for talented future physician-scientists to participate in a state-of-the-art translational research related to pediatric CV disease while acquiring the skills necessary to apply this experience to a broad range of future research topics. By the end of the training program, we anticipate that each fellow will be able to demonstrate objective achievement of the training core goals as demonstrated by a comprehensive understanding of his/her research area, by a record of publication in peer-reviewed journals, by the application for peer-reviewed support from external funding agencies, and by the transition from post-doctoral fellow status to a junior faculty position along a continued, mentored academic career path.
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PELEX-C: A high-resolution, wireless ECG system for infants/children
  • 批准号:
    7540873
  • 项目类别:
  • 资助金额:
    $16.67万
  • 财政年份:
    2008
  • 负责人:
    Bradley Barth Keller
  • 依托单位:
Engineered Early Embryonic Cardiac Tissue
Engineered Early Embryonic Cardiac Tissue
  • 批准号:
    7636845
  • 项目类别:
  • 资助金额:
    $37.0万
  • 财政年份:
    2008
  • 负责人:
    Bradley Barth Keller
  • 依托单位:
Engineered Early Embryonic Cardiac Tissue
  • 批准号:
    7884391
  • 项目类别:
  • 资助金额:
    $37.0万
  • 财政年份:
    2008
  • 负责人:
    Bradley Barth Keller
  • 依托单位:
国内基金
海外基金
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  • 批准号:
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  • 项目类别:
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  • 资助金额:
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  • 批准年份:
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    --
  • 项目类别:
    --
  • 资助金额:
    35万元
  • 批准年份:
    2020
  • 负责人:
    陈加祥
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ARTS在邻苯二甲酸(2-乙基己基)酯诱导的小鼠睾丸间质细胞凋亡中的作用及机理研究
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  • 项目类别:
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  • 批准年份:
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    81372444
  • 项目类别:
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  • 资助金额:
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  • 批准年份:
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