Clinical Sciences

临床支持核心(CSC)将支持和促进基础、临床和 行为科学家，涉及人类受试者和生物标本，并提供基础设施 这将加强和促进多学科发病机制和艾滋病毒/艾滋病翻译研究。从长远来看 CSC的总体目标是支持和加强多学科研究，以推动 针对艾滋病毒感染者或有感染艾滋病毒风险的个人的治疗和预防干预措施。 根据对迈阿密大学艾滋病毒/艾滋病调查人员的支持差距，CSC将把重点放在 促进和补充全校在发病机制和翻译方面的努力的三个具体目标 艾滋病毒/艾滋病研究。这些目标和提供的服务也将促进多学科合作 在艾滋病毒/艾滋病调查人员中。CSC的具体目标是：1.建立生物统计学分核心 致力于艾滋病毒/艾滋病研究；2.建立临床资料库和前瞻性纵向标本 建立未来发病机制和多学科研究的银行；3.建立安全监测 委员会和数据安全监测委员会，以满足人类受试者研究的新需求。 实现这些目标将满足未得到满足需求，并为我们的艾滋病毒/艾滋病提供附加值 通过几个切实的成果开展研究计划。预计这些结果将包括新的 研究和结果出版物，新赠款申请的初步数据，新的见解和方向 病因学/转化性研究，并促进新的多学科合作研究。此外， 临床资料库和标本库的建立将提供重要的机会和结果 附加值，包括对发病机制的新见解，促进创新的先导研究，提供 为新的赠款申请提供初步数据，促进新的多学科合作，并利用 基于现有的治疗和预防干预研究以及队列研究。 临床治疗和预防研究的贡献和进展是无与伦比的 在艾滋病毒临床科学的进步中。这些进步是由持续的能力播种的 做好病机和转译研究。CSC将与科学计划合作 以及D-CFAR在提供支持多学科研究的基础设施方面的核心领导地位 并在与人类有关的致病机制和翻译研究领域培养新的机会 研究对象。 表演场地(

The Clinical Support Core (CSC) will support and facilitate collaborative research among basic, clinical, and behavioral scientists that involves human subjects and biological specimens and provide an infrastructure that will enhance and facilitate multidisciplinary pathogenesis and translational HIV/AIDS research. The longterm overarching goal of the CSC is to support and enhance multidisciplinary research that will advance therapeutic and prevention interventions for individuals with HIV infection or at risk for HIV infection. Based on identified gaps in support to University of Miami HIV/AIDS investigators, the CSC will focus on three specific aims to facilitate and complement University wide efforts in pathogenesis and translational HIV/AIDS research. These aims and the services provided will also foster multidisciplinary collaborations among the HIV/AIDS investigators. The specific aims for the CSC are: 1. to establish a Biostatistics Subcore dedicated to HIV/AIDS research; 2. to establish a clinical repository and prospective longitudinal specimen bank for future pathogenesis and multidisciplinary research; and 3. To establish a Safety Monitoring Committee and a Data Safety Monitoring Board to meet the emerging needs of human subjects' research. The accomplishment of these aims will provide meet unmet needs and provide added value to our HIV/AIDS research programs through several tangible outcomes. These outcomes are anticipated to include new studies and resulting publications, preliminary data for new grant applications, new insights and directions in pathogenesis/translational research, and fostering new multidisciplinary collaborative studies. In addition, the establishment of clinical repository and specimen bank will provide significant opportunities and result in added value, including new insights into pathogenesis, promoting innovative pilot studies, providing preliminary data for new grant applications, fostering new multidisciplinary collaborations, and capitalizing upon existing therapeutic and preventive intervention studies, and cohort studies. The contributions and progress made by clinical therapeutic and prevention research have been unparalleled in the advancement of HIV clinical science. These advances have been seeded by the continuing ability to do pathogenesis and translational research. The CSC will work collaboratively with the Scientific Programs and the D-CFAR Core leadership in providing an infrastructure that will support multidisciplinary research and foster new opportunities in the areas of pathogenesis and translational research as it relates to human subjects. PERFORMANCE SITE(