Resistance Training as an Aid to Standard Smoking Cessation Treatment

描述（由申请人提供）：吸烟仍然是美国成年人中可预防的主要死亡原因；然而，大约20.9%的美国成年人仍在吸烟。对戒烟后体重增加和情绪相关戒断症状的担忧是已知的复发的预测因素。先前的大规模干预试验表明，运动是戒烟的有益辅助治疗，因为它对体重担忧和消极情绪状态都有积极影响。然而，这些试验中的大多数只关注女性，而且只关注有氧运动。阻力训练（如举重）也可能为吸烟者提供一种有益的辅助戒烟策略，因为它既可以改善情绪，又可以控制体重。因此，拟议的试点研究将测试阻力训练计划作为标准戒烟治疗对健康成年男性和女性吸烟者戒烟的帮助的有效性。具体来说，我们计划在60名健康男性和女性中比较标准戒烟治疗加12周阻力训练计划与相同标准戒烟治疗加等量接触控制的效果。戒烟结果（[长期]戒烟和点流行戒烟）将通过一氧化碳和自我报告来验证。治疗后12周和[3个月]两种情况戒烟率的差异将为充分支持的临床试验的有效性估计提供数据。吸烟是导致美国人死亡的第二大原因，美国每四个人中就有一个人死于吸烟。因此，这项建议是通过进一步阐明戒烟所涉及的行动机制来解决这一公共卫生问题的一项努力。它还具有发现另一种帮助吸烟者戒烟的方法的潜力。

DESCRIPTION (provided by applicant): Cigarette smoking continues to be the leading, preventable cause of death among American adults; however, approximately 20.9% of US adults continue to smoke. Concerns about weight gain and mood-related withdrawal symptoms following smoking cessation are known predictors of relapse. Previous large-scale intervention trials indicate that exercise is a beneficial adjunct treatment for smoking cessation, as it positively impacts both weight concerns and negative mood states. The majority of these trials, however, have focused only on women, and only on aerobic exercise. Resistance training (i.e., weight lifting), may also offer smokers a beneficial adjunctive strategy to quit smoking, as it too can both improve mood and manage body weight. As such, the proposed pilot study will test the efficacy of a resistance training program as an aid to standard smoking cessation treatment on cessation among healthy adult male and female smokers. Specifically, we plan to compare the effects of a standard smoking cessation treatment, plus a 12-week resistance training program to the same standard smoking cessation treatment plus equivalent contact control among 60 healthy men and women. Smoking cessation outcomes ([prolonged] abstinence and point prevalence abstinence) will be verified by carbon monoxide [and self-report.] Differences in post-treatment 12-week and [3-month] cessation rates between conditions will provide data for power estimates for an adequately powered clinical trial. Cigarette smoking is the second leading cause of death among Americans, as it is responsible for one out of every four deaths in the United States. As such, this proposal represents an effort to combat this public health problem by further elucidating the mechanisms of action involved in smoking cessation. It also carries the potential to discover an additional way to assist smokers in quitting smoking.