TIME-RESOLVED 3D QUANTITATIVE FLOW MRI OF VESSELSWITH PARALLEL IMAGING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 准确了解主要脑血管的血流特征对于诊断脑血管异常具有重要意义。这涉及血流动力学关键区域的评估以及生物力学参数（如壁面剪切应力和压力梯度）的推导。对于该项目，采用并行成像的时间分辨三维相位对比MRI方法，在心动周期的多个实例中测量三维血流。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Exact knowledge of blood flow characteristics in the major cerebral vessels is of great relevance for diagnosing cerebro-vascular abnormalities. This involves the assessment of hemodynamically critical areas as well as the derivation of biomechanical parameters like wall shear stress and pressure gradients. For this project a time-resolved, three-dimensional phase-contrast MRI method using parallel imaging was implemented to measure blood flow in three-dimensions at multiple instances over the cardiac cycle.