OPERATIONAL STATUS OF THE 24-ID-C BEAMLINE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 24-ID-C插入光束线去年的活动重点是： 1.结晶学调试测试表征良好的晶体(溶菌酶、索马汀等)微调光束线并对其进行优化，以获得最高质量的晶体数据。 2.通过增加新的软件和硬件能力，进一步加强光束线光学和控制部件。 3.过渡到全职用户数据收集 在结晶学调试期间对光束线进行的诊断测试已经证明，24-ID-C光束线能够从低R合并因子(约0.04，1.4？分辨率)的良好衍射晶体中产生高质量的结晶学数据。其他测试表明，在曝光时间低至100毫秒的情况下，数据质量没有恶化。在7000-9000 eV范围内收集的低能数据也表明，通过利用硫原子微弱的反常信号来解决结构问题是可行的，重申了从24-ID-C束线获得的高质量数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The last year's activities at the 24-ID-C insertion beamline have focused upon: 1. Crystallographic commissioning  testing well characterized crystals (lysozyme, thaumatin, etc.) to fine tune the beam line and to optimize it to get the highest quality crystallographic data. 2. Further enhancement of the beamline optical and control components with the addition of new software and hardware capabilities. 3. Transition to full-time user data collection Diagnostic testing of the beamline during crystallographic commissioning has proven the capability of the 24-ID-C beam line in producing high quality crystallographic data from well diffracting crystals with low R-merge factor (~0.04 for 1.4 ¿ resolution). Additional tests have demonstrated no deterioration in data quality for exposure times as small as 100 msec. Low-energy data collection in the range of 7000-9000 eV has also shown the feasibility of solving structures by employing weak anomalous signal from sulphur atoms, reiterating the high quality of data obtainable from the 24-ID-C beam line.