HPV Infection Among High-Risk Young Men in Puerto Rico

生殖器HPV感染是世界上最常见的性传播感染之一， 高流行率也可能导致艾滋病毒传播风险增加。虽然HPV 感染与男性和女性的慢性疾病后遗症有因果关系， 女性，对HPV感染和HPV分布的了解相对较少 与艾滋病毒状态有关的亚型。了解艾滋病的流行率、分布情况， HIV+和HIV-个体中HPV亚型的一般来源是 这对于了解HPV的长期健康后果至关重要。研究人员在 公共卫生学院全球健康研究中心 科学校园，波多黎各，与最大的公共资助的STI合作 岛上的诊所（拉丁美洲性传播中心） （CLETS））正在对性活跃人群中的毒品和性风险进行评估， 年轻男性吸毒者。采用民族流行病学方法， 行为研究和分子流行病学，与研究有以下几点 研究目的：1.患病率：比较肛门生殖器HPV的患病率 波多黎各HIV阳性和HIV阴性年轻男性吸毒者的临床样本感染 瑞可2.基因型变异性：比较HPV亚型在一个基于临床的 波多黎各的艾滋病毒阳性和艾滋病毒阴性年轻男性吸毒者样本。3.性风险 因素：比较艾滋病毒阳性和艾滋病毒阴性的年轻男性吸毒者，特别注意 性风险行为（例如，性行为，性伴侣），可能与 HPV亚型和/或HIV/HPV合并感染。

Genital HPV infection is one of the most commonly diagnosed STIs worldwide and its high prevalence may also contribute to increased HIV transmission risk. Although HPV infection has been causally linked with chronic disease sequelae both in men and women, relatively little is known about the distribution of HPV infection and HPV subtypes among in relation to HIV status. Understanding the prevalence, distribution, and general sources of HPV subtypes among both HIV+ and HIV- individuals is important for understanding long term health consequences of HPV. Researchers within the Center for Research on Global Health at the School of Public Health, Medical Sciences Campus, Puerto Rico, in collaboration with the largest publicly funded STI clinic on the island (Centro Latinoamericano de Enfermedades de Transmisi¿n Sexual (CLETS)), are conducting an assessment of drug and sexual risk among sexually active, young male drug users. Using an ethnoepidemiological approach that integrates behavioral research and molecular epidemiology, with the study has the following research objectives: 1. Prevalence: To compare the prevalence of anogenital HPV infection in a clinic-based sample of HIV+ and HIV- young male drug users in Puerto Rico. 2. Genotype Variability: To compare the distribution of HPV subtypes in a clinicbased sample of HIV+ and HIV- young male drug users in Puerto Rico. 3. Sexual Risk Factors: To compare HIV+ and HIV- young male drug users, with particular attention to sexual risk practices (e.g., sexual practices, sex partnering) that may be associated with HPV subtypes and/or HIV/HPV coinfection.