Explaining differences in birth size and adiposity between Pakistani and white babies.
Explaining differences in birth size and adiposity between Pakistani and white babies.
批准号:
G0601712/1
负责人:
Jane West
金额:
$26.32万
依托单位:
依托单位国家:
英国
项目类别:
Fellowship
财政年份:
2007
资助国家:
英国
项目状态:
已结题
起止时间:
2007 至 --
中文摘要
这项研究将检验巴基斯坦和白人婴儿出生尺寸的差异。在英国,南亚人与普通人群在出生尺寸、体脂比例以及患心脏病和糖尿病的风险方面存在差异。南亚人更有可能出生时身材矮小,在以后的生活中患心脏病和糖尿病。成人疾病的过程开始于生命早期,甚至可能在出生前。尽管体型较小,但南亚婴儿可能比白人婴儿有更多的体脂,这导致他们成年后患病的风险增加。我将阐明南亚成年人体内脂肪排列的差异是否可以在出生时看到。这项研究将使用出生在布拉德福德项目的数据和血液样本,这是一个独特的研究项目,追踪2007年至2009年在该市出生的1万名婴儿的生活。在这项研究中,我将使用5000个婴儿的数据。这项研究将对解决白人和南亚人口慢性成人疾病负担的努力作出重大贡献。
英文摘要
This study will examine differences in birth size between Pakistani and white babies. In the UK there are differences in birth size, body fat proportion and risk of heart disease and diabetes between south Asians and the general population. South Asians are more likely to be born small and develop heart disease and diabetes in later life. The processes of adult disease begin in early life, possibly even before birth. Despite their smaller size south Asian babies may have more body fat than white babies, which leads to their increased risk of disease as adults. I will clarify whether differences in the arrangement of body fat seen in south Asian adults, can be seen at birth. The study will use data and blood samples from the Born in Bradford project, a unique research programme following the lives of 10,000 babies born in the city between 2007 and 2009. In this study I will use data from 5,000 babies.The study will make a major contribution to efforts to tackle the burden of chronic adult disease in both white and south Asian populations.
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会议论文
Differences in growth and adiposity between UK Pakistani and White British children: the causes and consequences of smaller size and greater adiposity
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批准号:MR/K021656/1
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项目类别:Fellowship
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资助金额:$39.74万
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财政年份:2013
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负责人:Jane West
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依托单位:
海外基金