Clinical and Educational Core

临床和教育核心(CEC；核心2)将承担ExCITRA(P20)的四个主要组成部分的全中心责任，包括：1)所有人类研究参与者的招募、筛查、诊断评估和临床护理；2)成功满足资格标准的所有受试者的综合神经认知评估；3)同时进行的精神药理学表征 个人对刺激性自我给药(可卡因依赖者为可卡因)和/或给药(可卡因依赖者和健康对照组受试者为哌醋甲酯)的主观、行为和神经认知反应；以及，4)附属受训人员在 药物成瘾的跨学科和翻译神经生物学。

The Clinical and Educational Core (CEC; Core 2) will assume Center-wide responsibility for four major components of the ExCITRA (P20), including: 1) the recruitment, screening, diagnostic assessment, and clinical care of all human research participants; 2) the comprehensive neurocognitive assessment of all subjects successfully meeting eligibility criteria; 3) the concurrent psychopharmacologic characterization of individuals' subjective, behavioral, and neurocognitive responses to stimulant self-administration (cocaine in cocaine dependent subjects) and/or administration (methylphenidate in cocaine dependent and healthy control subjects); and, 4) the coordination of research career development of affiliated trainees in the interdisciplinary and translational neurobiology of drug addicfion.