Molecular Biology

分子生物学核心将为项目1 （Saper）、项目3 （Scammell）和项目5 （Chamberiin）提供专家和高效的实验室服务。Core B的主要职责是小鼠菌落的管理和基因分型，并进行原位杂交组织化学。随着技术的发展，Core B也将产生新的细菌克隆用于原位杂交和新的病毒载体。

The Molecular Biology Core will provide expert and efficient laboratory services to Project 1 (Saper), Project 3 (Scammell), and Project 5 (Chamberiin). The major duties of Core B are management and genotyping of mouse colonies and performing in situ hybridization histochemistry. Core B will also produce new bacterial clones for in situ hybridization and new viral vectors as technology evolves. Core B is designed to optimize efficiency, accuracy, and expertise. The Core will manage large, shared mouse colonies to ensure a reliable and efficient supply of accurately genotyped mice for each Project. The Core also will centralize the performance of complex molecular techniques such as in situ hybridization histochemistry and bacterial culture so researchers in the Projects can focus on the science instead of debugging techniques Our years of experience with these methods maximizes the likelihood that the complicated molecular techniques proposed in this PPG will succeed.