ctsa infrastructure for clinical trials

本分项目是CTSA供资的估计百分比，即 被用于广泛的研究领域(艾滋病研究、儿科研究或 临床试验)。列出的总成本仅是对CTSA金额的估计 用于这一研究领域的基础设施，而不是由 授予子项目或子项目工作人员的NCRR补助金。 梅奥诊所CTSA应用程序的目标是展示我们对创新临床和翻译研究活动的整合和扩展的愿景，以便在梅奥诊所发展一个功能强大的临床和翻译研究学术之家。这个新的临床和转译研究中心(CCTR)将建立在梅奥在临床和转译研究方面的长期卓越和承诺的基础上，其中包括对关键基础设施的支持和对职业发展的承诺。为了实现这一目标，我们描述了对CTSA关键要素的全面方法 RFA和重点是加强：1)向调查人员提供创新工具的临床研究核心资源；2)培养下一代调查人员的职业发展和教育计划；3)确保患者安全和隐私的合规和监管事务支持，以及支持调查团队的以客户服务为导向的方法；4)社区事务支持 加强临床和转化性研究的参与性、多样性和社区支持；5)与行业和临床实践合作，将研究发现转化为常规临床实践；以及6)继续和扩大机构支持，包括临床和转化性研究的“学术之家”。我们还提出了一项综合治理计划，该计划将强有力的 以数据为导向对CCTR的每个要素和整个计划进行评估。原则上，CTSA计划与梅奥诊所的历史、概念和哲学基础是一致的，在本申请中，我们清楚地阐明了我们对CTSA总体目标和变革目标的愿景 计划可在梅奥会面。此外，我们有“制度意愿”，并在文化上有权执行我们的计划。因此，梅奥已经准备好积极和迅速地实施CTSA计划；梅奥诊所CCTR将成为CTSA计划出现时一个功能强大和成功的“旗舰”网站 来自美国国立卫生研究院路线图。总之，梅奥临床和转化研究中心(CCTR)将汇集梅奥临床医学院内五所学校的所有资源，以及100多年的科学和医学研究专业知识，以发现创新的新方法，加速将研究成果转化为影响我们当地和国家社区所有成员的疗法、工具和患者护理实践。这一愿景与梅奥诊所的既定使命完全一致，即通过整合的临床实践、教育和研究，每天为每一位患者提供最佳护理。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of the Mayo Clinic CTSA application is to present our vision for the integration and expansion of our innovative clinical and translational research activities, so that a highly functional academic home for clinical and translational research is developed at the Mayo Clinic. This new Center for Clinical and Translational Research (CCTR) will be founded on Mayo's long-standing excellence in and commitment to clinical and translational research, which includes the support of key infrastructure and a commitment to career development. To achieve this goal we describe a comprehensive approach to the key elements of the CTSA RFA and focus on enhancing: 1) Clinical Research Core Resources that provide innovative tools to investigators; 2) Career Development and Education Programs that prepare the next generation of investigators; 3) Compliance and Regulatory Affairs Support that ensures patient safety and privacy, and customer service-oriented approaches to support investigative teams; 4) Community Affairs support to enhance participation, diversity and community support for clinical and translational research; 5) Collaboration with Industry and Clinical Practices to translate research discoveries into routine clinical practice; and 6) Continued and Expanded Institutional Support that includes an "academic home" for clinical and translational research. We also propose a consolidated governance plan that incorporates strong data-driven evaluation of each CCTR element and the program as a whole. In principle, the CTSA program is consistent with the historical, conceptual and philosophical underpinnings of Mayo Clinic, and in this application we clearly articulate our vision of how the overarching and transformative goals of the CTSA program can be met at Mayo. Additionally, we have the "institutional will" and are culturally empowered to execute our plan. Thus, Mayo is ready to implement the CTSA program aggressively and rapidly; the Mayo Clinic CCTR will be a highly functional and successful "flagship" site for the CTSA program as it emerges from the NIH Roadmap. To summarize, the Mayo Clinic Center for Clinical and Translational Research (CCTR) will bring together all the resources of the five schools within the Mayo Clinic College of Medicine, and more than 100 years of scientific and medical research expertise, to discover innovative new methods that will speed the translation of research results into therapies, tools and patient care practices that impact all members of our local and national communities. This vision is entirely consistent with the stated mission of the Mayo Clinic to provide the best care to every patient every day.through integrated clinical practice, education and research.