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中文摘要
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简介(由申请人提供):自2002年以来,美国国家经济研究局(NBER)每年春季组织并举办为期一天的队列研究工作组研讨会。这些研讨会汇集了大约15-20位学者,他们对分析衰老过程中的生命历程事件有共同的兴趣;累积暴露在衰老相关结果中的作用;了解不同人群的经济,制度和人口背景是如何变化的,以及不同种族,民族,性别和群体中的社会经济群体。队列研究工作组研究了不同的队列——不同的出生年份和不同的国家——以了解衰老过程中的生命过程事件。通过研究生命周期事件如何影响这些不同队列的老年结局,将有可能评估生命周期事件如何与环境相互作用以影响老年结局。这也将有可能确定是否有某些生物和行为反应是衰老过程的正常组成部分,以及这些反应的可塑性有多大。最后,检查发达国家过去的队列可以帮助阐明发展中国家可能发生的变化。本申请要求NIA提供资金,以两种关键方式建立年度队列研究会议。首先,我们建议将工作坊从一天延长到两天。第二,拨款将使我们能够支持更广泛的学者群体的参与,而不是仅仅依靠国家经济研究局的资金。该小组将包括来自美国大量研究型大学(包括nia支持的老龄化人口和经济中心)的学者,他们与NBER无关,但从事老龄化和生命过程研究;不同国家研究老龄化和生命历程的研究人员;非经济学研究背景的学者(如社会学、人口学、流行病学、临床医学、心理学、地理学);政府机构或非大学组织的研究人员;新研究者发展或扩大他们在老龄化和生命过程方面的研究议程;在美国和国外具有出生队列或其他长期纵向研究专长的研究人员;研究人员正在开发新的方法工具来研究纵向数据集。该应用程序还将使NBER能够扩展队列研究项目的内容,包括统计方法、流行病学和生物学的最新进展,以及关于特定纵向数据集的临床研究和报告,包括新的纵向数据集的可用性和对现有纵向数据集的扩展。
英文摘要
DESCRIPTION (provided by applicant): The National Bureau of Economic Research (NBER) has been organizing and hosting one day workshops of its Cohort Studies Working Group each year in the spring since 2002. The workshops bring together roughly 15-20 scholars with a common interest in analyses of life course events in aging; in the role of cumulative exposures in aging-related outcomes; and in understanding how the economic, institutional, and demographic context has changed for different cohorts and for different racial, ethnic, gender, and socioeconomic groups within cohorts. The Cohort Studies Working Group studies different cohorts - across birth years and across countries - to understand life course events in aging. By examining how life cycle events have affected the older age outcomes of these different cohorts, it will be possible to evaluate how life cycle events interact with the environment to affect older age outcomes. It will also be possible to identify whether there are certain biological and behavioral responses that are a normal part of the aging process and how malleable these responses are. Finally, examining past cohorts in developed countries can help elucidate the changes that may happen in developing countries. This application requests funds from NIA to build on the annual Cohort Studies meetings in two crucial ways. First, we propose to expand the workshop from one day to two. Second, grant funds would allow us to support the participation of a broader group of scholars than would be possible with NBER funds alone. This group would include scholars not affiliated with NBER but engaged in aging and life course research from a large number of research universities in the United States (including NIA-supported Centers on the Demography and Economics of Aging); researchers working on aging and the life course in different countries; scholars from research backgrounds other than economics (such as sociology, demography, epidemiology, clinical medicine, psychology, and geography); researchers at government agencies or non-university organizations; newer investigators developing or expanding their research agenda in aging and the life course; researchers with expertise in birth cohort or other long-term longitudinal studies in the U.S. and abroad; and researchers developing new methodological tools for the study of longitudinal data sets. This application would also enable the NBER to expand the content of the Cohort Studies program to include presentations on recent advances in statistical methodologies, in epidemiology and biology, and in clinical studies and reports on specific longitudinal datasets, including the availability of new longitudinal datasets and expansions to existing longitudinal datasets. PUBLIC HEALTH RELEVANCE: Understanding the role of life course events has implications for public health investments. The proposed annual meetings will influence research in this area by providing opportunities for interactions across different disciplines, enabling collaborative research, and by allowing researchers to learn from different disciplines, potentially influencing the way they work.
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会议论文
The Persistence of Longevity Across Generations: An Exploratory Investigation of Grandchildren of ex-POWs
The Persistence of Longevity Across Generations: An Exploratory Investigation of Grandchildren of ex-POWs
Life Course Events in Aging
Life Course Events in Aging
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: