CORE--MASS SPECTOMETRY

核心的使命是提供分析服务，并开发新的分析和技术，以支持CNRU研究人员发展对营养吸收，代谢和周转的理解。质谱核心提供了大多数独立研究人员通常无法获得的仪器和技术，实际上对这些研究人员的成功至关重要。该中心还在开发诊断工具，以预测疾病并监测疾病和治疗的进展。此外，我们为感兴趣的CNRU研究人员提供全面的指导，以提高他们对我们高度复杂的技术和仪器的熟练程度。在过去的一年里，CNRU研究人员通过Core提供的仪器范围大大扩大，现在包括气相色谱-质谱、同位素比质谱、LC-MS、LC-MS/MS、LCMS/离子阱（包括蛋白质组学研究所需的所有组件）、飞行时间质谱、二维凝胶电泳设备和软件、带MS引导自动自动进样器的制备型HPLC、2台核磁共振谱仪，用于细胞和组织代谢的生化分析（代谢组学）和动物MRI。

The mission of the core is to provide analytical services and to develop new assays and technology to support CNRU investigators to develop an understanding of nutrient absorption, metabolism, and turnover. The Mass Spectrometry Core furnishes instruments and technologies that would not normally be available to most independent investigators and is, in fact, essential to the success of these investigators. The core is also developing diagnostic tools to predict disease and to monitor progress of disease and treatment. In addition, we provide comprehensive instruction for interested CNRU investigators in order to increase their proficiency in our highly complex technologies and instrumentation. The range of instrumentation available to CNRU investigators through the Core has significantly expanded during the last year and now includes GC-MS, isotope ratio MS, LC-MS, LC-MS/MS, LCMS/iontrap (with all components required for proteomics research), time-of-flight mass spectrometry, two-dimensional gel electrophoresis equipment and software, preparative HPLC with MS-guided automatic autosampler, 2 NMR spectrometers for biochemical profiling of cell and tissue metabolism (metabolomics) and animal MRI.