Impact of BDNF Genotypes and Stress on Learning and Brain Development

描述（由申请人提供）：行政和数据管理核心（ADM戈尔）对整个中心（项目I、II、III）的运作至关重要。核心将管理和维护中心数据，促进项目之间的科学互动，并促进中心的教育活动。ADM核心的主要活动之一是中心的数据库维护（行为、遗传和成像），以及为项目1、11和III提供备份和IT服务。它将作为中心的数据管道，接收处理后的数据（成像和行为），维护它，并将其提供给所有其他核心，包括用于数据分析的统计遗传学核心。ADM Core代表一个单一的管道，负责处理人类DNA，并通过通用识别号指示哪些受试者具有所需的等位基因，并应联系项目I和II的成像部分。这种方法使数据能够以科学公正和符合HIPAA的方式收集和维护，具有成本效益和可靠性。行政管理核心将协调中心的互动，包括在纽约举行的项目计划年度会议和两年一次的中心咨询委员会会议，会上将审查项目的进展和结果，并讨论未来的计划。核心还将维护中心的网站www.sacklerinstitute.org/Cornell/。与中心有关的出版物将按照现行出版标准提供下载。工具和分析也将在这个网站上提供，将链接到所有项目的教师和研究员。除了这些支持功能外，ADM核心的最后一个关键职责是协调和监督与中心教育计划有关的活动。对中心的研究和方法感兴趣的个人（例如，研究生，博士后研究员，研究助理）将通过参加年度中心会议和培训研讨会，并通过直接合作中心支持的研究，接受中心支持的教育。此外，教育举措将通过与威尔康奈尔医学院的四个培训项目（神经科学研究生项目，三机构医学博士，哲学博士、儿科住院医师计划和精神病住院医师计划）。最后，ADM核心将负责协调萨克勒暑期研究所的活动，该研究所提供有关该中心方法的培训，包括神经影像学，遗传学和动物行为模型。

DESCRIPTION (as provided by applicant): The Administrative and Data Management Core (ADM Gore) is crucial to the functioning of the entire Center (Projects I, II, III). The Core will manage and maintain Center data, facilitate scientific interactions among projects, and promote the educational initiatives of the Center. One of the primary activities of the ADM core is database maintenance (behavioral, genetic, and imaging) for the Center, as well as providing back-up and IT services to Projects 1,11, & III. It will serve as a data conduit for the Center, receiving processed data (imaging and behavioral), maintaining it, and making it available for all other cores, including the Statistical Genetics Core for data analysis. The ADM Core represents a single pipeline that is responsible for processing human DNA and indicating, via universal identification number, which subjects have the desired alleles and should be contacted for the imaging portion of Projects I & II. This approach enables data to be collected and maintained in a scientifically-unbiased and HIPAA-compliant way that is cost effective and reliable. The ADM core will coordinate Center interactions, including the Annual Conference of the Project Pis and biennial Center Advisory Board in New York, at which project progress and results will be reviewed and future plans discussed. The Core will also maintain the Center's website www.sacklerinstitute.org/Cornell/. Center-related publications will be made available for download in compliance with current publishing standards. Tools and assays will also be made available on this site as will links to all project faculty and fellows. In addition to these support functions, the final critical responsibility of the ADM Core will be to coordinate and oversee activities relating to the Center's Educational Initiative. Individuals interested in the research and methods of the Center (e.g., graduate students, postdoctoral fellows, research assistants) will receive Center supported education through attendance of annual Center meetings and training workshops and through direct collaboration on Center supported research. Additionally, educational initiatives will be fostered through interactions with four training programs at the Weill Cornell Medical College (the Neuroscience Graduate Program, the Tri-lnstitutional M.D., Ph.D., the Pediatric Residency Program, and the Psychiatric Residency Program). Finally, the ADM Core will be responsible for coordinating the activities of the Sackler Summer Institute that provides training on the methods of the Center, including neuroimaging, genetics, and animal models of behavior.