HIV AND SUBSTANCE ABUSE LABORATORY CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 在过去五年中，该实验室核心设施的目标是建立所需的人力和物力资源，以支持艾滋病毒/艾滋病和滥用药物领域的研究。 专业人员和研究技术（核酸提取和扩增、基因分型、流式细胞术、蛋白质组学、微阵列以及细胞因子和趋化因子定量）已可用于免疫学、药物滥用和与艾滋病毒/艾滋病有关的传染病领域的研究。 两名外部顾问（Madhavan Nair博士和Avindra Nath博士）和三名导师（Salin Merali博士、Robert Donahoe博士和Geoffrey Stone博士）现在可以提供指导和有效开发项目，并在此过程中促进与当地和外部研究人员的合作。 为标本储存库以及用于监测该储存库的信息系统提供了支助。 提高科学生产力（5份出版物，9份出版物已付印并提交，12次在科学会议上发言，处理了1，000多份样品）。 此外，这一核心设施的服务现已扩大到包括逆转录病毒研究中心、PR艾滋病毒健康差异综合中心和成瘾研究中心。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the last five years, the goal of this laboratory core facility has been to establish needed human and physical resources to support research studies in the area of HIV/AIDS and substances of abuse. Specialized personnel and research technology (nucleic acid extraction and amplification, genotyping, flow cytometry, proteomics, microarray, and cytokines and chemokines quantification) have become available to research studies in the areas of immunology, drugs abuse and HIV/AIDS related infectious diseases. Two external consultants (Drs. Madhavan Nair and Avindra Nath) and three mentors (Drs. Salin Merali, Robert Donahoe and Geoffrey Stone) are now available for guidance and effective development of the projects and in doing so, foster collaborations with local and external researchers. Support for the specimen repository as well as for the informatics system used for monitoring this repository has been provided. Improved scientific productivity (five publications, nine, publications in press and submitted, and 12 presentations in scientific meetings and more that 1,000 samples processed). In addition, service of this core facility has now been extended to include the Retrovirus Research Center, the PR Comprehensive HIV Health Disparity Center and the Center for Addiction Studies.