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中文摘要
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描述(由申请人提供):本申请响应RFA-OD-09-005,“恢复法案有限竞争:支持新教师招聘,通过生物医学研究核心中心增加研究资源”(P30)。我们建议在干细胞研究领域聘请一名新的助理教授,对神经干细胞生物学或间充质干细胞生物学有特殊兴趣,作为圣安东尼奥细胞和分子灵长类动物研究所(SAICMP)的研究员,生物医学核心中心,以及UTSA生物系,作为终身助理教授。UTSA是该拉丁美洲地区教育的一般指导方针下的合格机构,并且是该拉丁美洲地区教育的特别目标机构,是为拉丁美洲人服务的机构。SAICMP的使命是促进互动研究,利用灵长类动物和其他相关的模型系统来研究干细胞及其分化衍生物的基本生物学,特别是优化和测试潜在的治疗应用于人类患者的方案。过去涉及过早应用基因治疗或最近基于干细胞的治疗应用于人类患者的经验表明,在通过相关动物模型系统的临床前测试确保其有效性和安全性之前,将这些方案应用于人类是危险的。我们为新聘的助理教授(终身教职)提供了一个极好的机会,有很强的机构支持和在学术界和生物医学研究领域取得巨大成功的职业发展潜力。我们承诺广泛的机构支持,包括持续的国家支持工资,个人实验室空间,终身职位,获得SAICMP所有成员,生物系教师和/或UTSA科学学院教师提供的所有资源,并有机会加入一个独特的干细胞生物学家团队,研究独特的,但高度相关的非人灵长类动物模型,用于干细胞治疗方法的研究。因此,这一申请通过寻求资金来响应RFA,这些资金将允许创建一个在来年无法获得的职位(工作)。
英文摘要
DESCRIPTION (provided by applicant): This application responds to RFA-OD-09-005, "Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers (P30). We propose to hire a new Assistant Professor in the area of Stem Cell Research, with a specific interest in either Neurological Stem Cell Biology or Mesenchymal Stem Cell Biology as an Investigator in the San Antonio Institute for Cellular and Molecular Primatology (SAICMP), a Biomedical Core Center, and the Department of Biology at UTSA, as a tenure-track Assistant Professor. UTSA is an Eligible Institution under the general guidelines of this RFA, and is a specifically targeted institution for this RFA as an Hispanic-Serving Institution. The mission of the SAICMP is to promote interactive research utilizing primate and other relevant model systems to investigate the basic biology of stem cells and their differentiated derivatives, and especially to optimize and test protocols for potential therapeutic application in human patients. Past experiences involving the premature application of either gene therapy or more recent stem-cell-based therapeutic applications to human patients have demonstrated the dangers of adapting these protocols to humans prior to ensuring their efficacy and safety by pre-clinical testing in relevant animal model systems. We define an excellent opportunity for a new hire at the Assistant Professor (tenure-track) level, with very strong institutional support and potential for development of a highly successful career in academia and biomedical research. We commit extensive institutional support in terms of ongoing state-supported salary, individual laboratory space, a tenure-track position, access to all resources afforded to all members of the SAICMP, the Department of Biology faculty, and/or the College of Sciences faculty at UTSA, and the opportunity to join a unique team of stem cell biologists working with a unique, but highly relevant nonhuman primate model for studies of stem-cell-based therapeutic approaches. Thus, this application is responsive to the RFA by seeking funds that will allow the creation of a position (job) that will not otherwise be made available during the coming year.
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Germline-mediated Transgenerational Epigenetic Inheritance of Paternal Epimutations Induced by a High Fat Diet
Germline-mediated Transgenerational Epigenetic Inheritance of Paternal Epimutations Induced by a High Fat Diet
Germline-mediated Transgenerational Epigenetic Inheritance of Paternal Epimutations Induced by a High Fat Diet
Epimutations in Offspring Produced by Assisted Reproductive Technologies (ART)
  • 批准号:
    8757199
  • 项目类别:
  • 资助金额:
    $62.76万
  • 财政年份:
    2014
  • 负责人:
    John R MCCARREY
  • 依托单位:
海外基金