Gordon Conf: Mammalian Gametogenesis & Embryogenesis

描述(由申请人提供)：了解产生可存活卵子和精子以及启动胚胎发育的分子机制对于动物物种在21世纪及以后的继续生存至关重要。生殖生物学的进展立即得到应用，不仅用于治疗人类不孕不育和亚生育，而且还用于改进避孕方法、农业工程的进展和野生动物保护的新方法。此外，由于多能细胞、配子和早期胚胎为旨在理解核编程和细胞周期调控以及转录、翻译和翻译后调控机制的基础研究提供了重要的模型，这些领域具有广泛的生物医学应用的潜在意义。关于哺乳动物配子发生和胚胎发生的戈登会议的目标是为交流该领域的最新进展提供一个论坛，并通过提供促进互动的宽松环境来促进讨论和辩论。戈登会议背景的一个特别重要的方面是年轻和成熟的研究人员以及国内和国际科学家的融合，以促进交流，从而产生新的想法，促进该领域的新合作。本次会议将讨论三个主要目标：1)展示前沿和发人深省的研究；2)促进临床医生和基础科学家之间的互动；3)促进该领域初级研究人员的职业发展。

DESCRIPTION (provided by applicant): Understanding the molecular mechanisms underlying the production of viable eggs and sperm and the initiation of embryonic development is essential for the continued survival of animal species in the 21st century and beyond. Advances in reproductive biology have immediate application, for not only the treatment of human infertility and subfertility, but also for improvements in developing contraceptive methods, advances in agricultural engineering and novel approaches to wildlife preservation. Moreover, as pluripotent cells, gametes and early embryos provide important models for basic research aimed at understanding nuclear programming as well as cell cycle regulation, and transcriptional, translational, and post-translational control mechanisms, and these areas have potential significance for a wide variety of biomedical applications. The objective of the Gordon Conference on Mammalian Gametogenesis and Embryogenesis is to provide a forum for the exchange of the latest advances in the field, as well as to promote discussion and debate by providing a relaxed setting that fosters interaction. A particularly important aspect of the Gordon Conference setting is the blending of young and established investigators, as well as national and international scientists to promote exchanges that will generate new ideas and foster new collaborations in the field. This conference will address three primary goals: 1) Presentation of cutting edge and thought-provoking research; 2) Fostering interactions between clinicians and basic scientists; and 3) Fostering career development of junior investigators in this field.