New Faculty Recruitment in Stem Cell and Regenerative Cardiovascular Biology

描述（由申请人提供）：威斯康星州医学院（MCW）的心血管中心（CVC）是一个生物医学核心中心，正在进行与心脏、肺、中风、高血压和肾损伤、糖尿病和肥胖相关的复杂心血管疾病的预防、检测、治疗和治愈相关的研究。最新的战略计划将MCW心血管研究活动的扩展指定为最高优先事项之一。最近分配扩大的研究空间和资源，以CVC招聘新的教师表明，这种扩张的制度支持。我们已经确定了一位令人兴奋的年轻科学家Aron Geurts博士，他将推进我们的目标，即在干细胞和再生心血管生物学方面开发一个卓越的创新研究项目。Geurts博士在细胞培养和技术开发方面拥有十年的经验，过去三年一直在人类和分子遗传学中心（HMGC）担任博士后研究员，在霍华德雅各布博士的实验室工作。他领导了我们的NHLBl-PGA计划的基因陷阱转座子诱变在大鼠中的开发和应用;使用锌指核酸酶创建第一个靶向敲除大鼠;以及将大鼠成纤维细胞重编程为诱导多能干细胞。这个PSO赠款将使立即有机会提供启动资金和保护的时间为博士Geurts作为一个新的终身教职员工，以发展自己的研究计划，成为一个独立资助，NIH支持的调查。Geurts博士不仅具有特殊的科学技能和能力，而且具有出色的协作能力，这使他成为招聘的强有力候选人，以增强CVC与生理学、细胞生物学、神经生物学和解剖学系以及生物工程和生物技术中心开发的干细胞和再生心血管生物学领域的研究资源。在这个校园的广泛资源将为博士提供独立的途径Geurts，而在同一时间扩大该机构的多学科研究人员的社区专注于NHLBI的具体利益。 CVC已经确定了一位令人兴奋的年轻科学家。Aron Geurts博士，他将推进我们的目标，在干细胞和再生心血管生物学方面开发一个卓越的创新研究项目。Geurts博士的招募将增强MCW CVC在干细胞和再生心血管生物学领域的研究资源。

DESCRIPTION (provided by applicant): The Cardiovascular Center (CVC) at the Medical College of Wisconsin (MCW) is a Biomedical Core Center with ongoing research related to the prevention, detection, treatment and cure of the complex set of cardiovascular diseases related to heart, lung, stroke, high blood pressure and renal injury, diabetes, and obesity. The most recent Strategic Plan designated the expansion of the cardiovascular research activities at MCW to be one of the highest priorities. Recent allocation of expanded research space and resources to the CVC to recruit new faculty demonstrates the institutional support of this expansion. We have identified an exciting young scientist, Dr. Aron Geurts, who would advance our goals to develop an innovative research program of excellence in stem cell and regenerative cardiovascular biology. Dr. Geurts with ten years of experience in cell culture and technology development, has been a postdoctoral fellow for the past three years in the Human and Molecular Genetics Center (HMGC) working in the laboratory of Dr. Howard Jacob. He has led the development and application in rats of gene-trap transposon mutagenesis for our NHLBl-PGA program; the creation of the first targeted knockout rats using zinc-finger nucleases; and the reprogramming of rat fibroblasts into induced pluripotent stem cells. This PSO grant would enable the immediate opportunity to provide start-up funds and protected time for Dr. Geurts as a new tenure-track faculty member to develop his own research initiatives to become an independently-funded, NIH-supported investigator. Not only his specific scientific skills and prowess but also his remarkable collaborative abilities make Dr. Geurts a strong candidate for recruitment to enhance research resources in the area of stem cell and regenerative cardiovascular biology developed by the CVC together with the Departments of Physiology, and Cell Biology, Neurobiology and Anatomy, the HMGC, and the Bioengineering and Biotechnology Center. The extensive resources on this campus would provide a pathway of independence for Dr. Geurts while at the same time expanding the institution's community of multidisciplinary researchers focusing on the specific interests of the NHLBI. The CVC has identified an exciting young scientist. Dr. Aron Geurts, who would advance our goals to develop an innovative research program of excellence in stem cell and regenerative cardiovascular biology. The recruitment of Dr. Geurts would enhance research resources in the area of stem cell and regenerative cardiovascular biology for the CVC at MCW.