RTMS AS A TREATMENT FOR FOCAL HAND DYSTONIA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 局灶性手部肌张力障碍(FHD)是一种以手部肌肉不自主收缩和协同收缩为特征的疾病。越来越多的证据表明，单一的rTMS治疗可以暂时改变大脑的兴奋性，并使FHD患者的症状得到暂时改善。这项建议的具体目的是收集关于长期rTMS治疗与假rTMS治疗在10名FHD患者中的疗效的试点数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Focal hand dystonia (FHD) is a disorder characterized by involuntary contraction and co-contraction of muscles of the hand. There is growing evidence that a single treatment of rTMS can transiently modify brain excitability and produce temporary symptom improvement in people with FHD. The specific aim of this proposal is to collect pilot data regarding the efficacy of longer-term rTMS treatment vs. sham rTMS in ten subjects with FHD.