A LONGITUDINAL STUDY OF CEREBRAL AND NEUROCOGNITIVE FUNCTION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究将试图更多地了解艾滋病毒对大脑的身体和精神影响，并确定谁可能处于与大脑有关的困难的风险较高的情况。这项研究将通过一种名为磁共振光谱的想象测试来观察不同大脑化学物质的数量，以及不同大脑区域的大小。将该测试的结果与本研究期间完成的神经学和神经心理学测试进行比较。 将询问已入组加州NeuroAIDS组织网络研究的合格受试者是否愿意参加本研究。如果愿意，他们只会进行MRS。CNTN研究收集的数据将用于与MRS进行比较。 将进行筛选访视，在此期间将采集他们的药物和病史，并采集一汤匙血液进行常规实验室检查。女性将接受妊娠试验，如果怀孕则不参加。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will try to learn more about physical and mental effects of HIV on the brain and determine who may be at a higher risk of difficulties related to the brain. The study will observe the amount of different brain chemicals, and the size of different brain regions by doing an imagining test called magnetic resonance spectroscopy. Results from this test will be compared to neurological and neuropsychological tests completed during this study. Eligible subjects already enrolled in the California NeuroAIDS Tissue Network study will be asked if they are willing to participate in this study. If willing, they will have MRS only performed. The data that is being collected for the CNTN study will be used to compare with the MRS. A screening visit will be done, during which their medication and medical history will be taken, and one tablespoon of blood will be taken for routine laboratory tests. Women will have a pregnancy test and will not participate if pregnant.