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A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE

A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE
尿苷 II/III 期、随机、双盲、安慰剂对照试验
批准号：
7951562
负责人：
Judith S. Currier
金额：
$2.06万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2009-11-30
来源：
https://reporter.nih.gov/project-details/7951562
关键词：
ClinicalClinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseFatty acid glycerol estersFundingGrantInstitutionLimb structureLipoatrophyMeasuresPhasePlacebosRandomizedResearchResearch PersonnelResourcesSourceSupplementationUnited States National Institutes of HealthUpper armUridinedouble-blind placebo controlled trial

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 具体目标： 主要目标： 通过比较尿苷组和安慰剂组从基线到48周的DEXA(双能X射线吸收法)测量的肢体脂肪的变化，来检验补充尿苷对临床脂肪萎缩的HIV-1感染者肢体脂肪的影响。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. SPECIFIC AIMS: Primary Objective: ¿¿ To examine the effect of uridine supplementation on limb fat in HIV-1-infected subjects with clinical lipoatrophy, by comparing changes from baseline to week 48 in DEXA (dual-energy x-ray absorptiometry)-measured limb fat between the uridine arm and placebo arm.
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