SOFTWARE DVMT, DOCUMENT & DISSEM WEB PAGES OF INFO ON MULTI SCALE MODELING TOOLS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 维护MMTSB网页（http：mmtsb.scripps.edu）是为了向科学界提供网络服务，分发和支持在资源内开发的软件工具，提供关于MMTSB资源及其项目的一般信息，并提供相关资源的选定链接。已经提供的网络服务包括非常成功和建立的病毒粒子资源管理器数据库（VIPERdb），以及一些实用功能的核酸和蛋白质建模应用程序，特别是简化的晶格模型和全原子表示和Go模型服务器之间的相互转换。 MMTSB网站本身是MMTSB工具集的分发站点，该工具集正在开发用于多尺度蛋白质建模和结构预测应用。它是一个模块的集合，大部分是用perl编写的，以确保可移植性，并允许轻松修改和扩展。该工具集提供了CHARMM、Amber、MONSSTER、PSIRED和MODELLER的接口，专门面向蛋白质和核酸建模应用，并实现了在模型相互转换和高级采样技术资源中开发的新方法。该工具集的设计是高度模块化的，提供易于使用的面向应用的实用程序以及灵活的编程接口，用于更复杂的定制应用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The MMTSB web pages (http://mmtsb.scripps.edu) are maintained to provide web services to the scientific community, distribute and support software tools developed within the resource, offer general information about the MMTSB resource and its projects, and provide selected links to related resources. Already available web services include the very successful and established Virus Particle Explorer Database (VIPERdb) as well as some utility functions for nucleic acid and protein modeling applications, in particular for interconversion between reduced lattice models and all-atom representation and the Go-model server. The MMTSB web site itself is the distribution site for the MMTSB Tool Set that is being developed for multiscale protein modeling and structure prediction application. It is a collection of modules, mostly written in perl to ensure portability and allow for easy modifications and extensions. This tool set provides interfaces to CHARMM, Amber, MONSSTER, PSIRED and MODELLER specifically geared towards protein and nucleic acid modeling applications and implements new methods developed within the resources for model interconversion and advanced sampling techniques. The design of the tool set is highly modular offering easy-to-use application-oriented utilities as well as flexible programming interfaces for more complex customized applications.