ALCOHOL EFFECTS ON THE ADOLESCENT BRAIN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 该项目正在进行中，其目的是使用纵向双胞胎对照设计研究48对同卵双胞胎，以评估酒精和药物使用对大脑结构和功能的影响。该项目使用了一套全面的、互补的神经心理学、心理生理学和MRI评估方法。MRI成像包括用于形态测量分析的高分辨率结构成像和在表现出对奖励敏感的神经区域敏感的任务期间的全脑功能成像。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. he purpose of the project, which is ongoing, is to study 48 pairs of monozygotic twins using a longitudinal cotwin-control design to assess effects of alcohol and drug use on brain structure and function. The project uses a comprehensive and complementary battery of neuropsychological, psychophysiological and MRI assessment. MRI imaging includes high-resolution structural imaging for morphometric analyses and whole-brain functional imaging during performance of a task shown to be sensitive to reward-sensitive neural areas.