Core--Mathematical and Statistical Analysis

数学和统计分析与建模核心的目的是提供 为所有项目所需的数量支持提供有效的组织 中心。需要的支持范围包括实验设计和数据分析， 统计建模、机理模型建立、随机建模和模型求解。 具体应用包括流体流动和污染物传输、修复的模型 污染环境、暴露评估以及统计和生理方面的 基于药代动力学模型。核心由定量的、跨学科的 具有确定性和统计建模、生物统计学、 应用数学和计算机科学。总体而言，该小组将提供量化 通过应用已知的方法和途径提供支持。它还将提供 领导中心调查领域的方法开发，特别是 需要创新的建模方法。

The purpose of the Mathematical and Statistical Analysis and Modeling Core is to provide an efficient organization for the quantitative support required by all projects in the Center. The range of support needed includes experimental design and data analysis, statistical modeling, mechanistic model formulation, stochastic modeling, and model solution. Specific applications include models of fluid flow and contaminant transport, remediation of contaminated environments, exposure assessment, and statistical and physiologically based pharmacokinetic modeling. The Core comprises a quantitative, interdisciplinary team with backgrounds in deterministic and statistical modeling, biostatistics, applied mathematics, and computer science. Collectively, this group will provide quantitative support through application of known methods and approaches. It will also provide leadership in method development for areas of investigation in the Center with particular need for innovative modeling approaches.