NEURAL CORRELATES OF AUDITOR FILL IN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 一个基本的问题是：如何在复杂的声学环境中分离和分析发声对象？ 通过结合行为和生理学，仔细制定行为问题，并使用基于信号检测理论的分析，我们将实现三个目标。 目的1：测量和比较猕猴和人类的看法填补。 目标1将通过测量猕猴和人类的能力来实现，以检测前景声音的连续性，作为插入其中的间隙的持续时间和中断噪声的强度的函数。 目标二：使用分析来确定填补的神经相关性，从而允许直接比较听觉皮层神经元对目标1结果的反应。 目的3：确定多个皮层区域的神经反应与行为表现和决策之间的关联强度。 为了实现目标2和3，将使用基于信号检测理论的分析-类似于前一段中关于视觉系统的分析。 实现这些目标将大大促进对听觉感知和决策的神经反应贡献的理解。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A fundamental question is: How can one segregate and analyze a sound-producing object in a complex acoustic environment? By combining behavior and physiology, carefully framing the behavioral question, and using signal detection theory based analyses we will achieve three aims. Aim 1: To measure and compare macaque and human perceptions of fill-in. Aim 1 will be achieved by measuring macaques' and humans' abilities to detect the continuity of foreground sounds as a function of the duration of gaps inserted into them and the intensity of an interrupting noise. Aim 2: To determine neural correlates of fill-in using analyses that allow for direct comparisons of auditory cortical neurons' responses to the results of Aim 1. Aim 3: To determine the strength of association between neural responses and behavioral performance and decisions in multiple cortical fields. To achieve Aims 2 nd 3, signal detection theory based analyses--similar to analyses referred to in the previous paragraph about the visual system--will be used. Achieving the aims will significantly advance the understanding of neural responses contributions to auditory perceptions and decision-making.