COBRE: LSU: NEUROCHEM OF LIPID MESSENGERS CORE RESOURCE MODULE: RADIOCHEM TECH

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 脂质信使神经化学核心资源模块（NCLM）由维克托Marcheselli指导，他是一位在脂质第二信使分析方面具有丰富经验的研究者。NCLM允许核心参与者通过放射化学和色谱技术（TLC、HPLC和GLC）测量内源性脂质信使的数量，并在刺激后跟踪脂质介导剂的代谢。 核心小组还在数据解释方面提供技术支持和援助。 核心容纳了一个新的LC-MS/MS，该系统部分是用COBRE中要求的资金购买的，部分是由LSU提供的匹配资金购买的。 该仪器允许识别在拟议项目的实验中识别和研究的新生物活性脂质。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Neurochemistry of Lipid Messengers Core Resource Module (NCLM) is directed by Victor Marcheselli, an investigator who has extensive experience in analysis of lipid second messengers. The NCLM allows core participants to measure by radiochemical and chromatographic techniques (TLC, HPLC and GLC) quantities of endogenous lipid messengers as well as to follow the metabolism of lipid mediatorss after stimulation. The core also provides technical support and assistance in interpretation of the data. The core houses a new LC-MS/MS that was purchased in part with funds requested in the COBRE and in part by matching funds from LSU. This instrument allows identification of new bioactive lipids identified and studied in the experiments of the proposed projects.