COMPUTATIONAL BIOLOGY & BIOINFORMATICS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目侧重于计算生物学和生物信息学的基础设施发展，作为塔斯基吉大学生物医学研究中心(CBR)核心资源的一部分。涉及先进信息技术、互联网和数据库的研究对于检查和分析疾病发生模式、遗传特征和分子水平动力学至关重要。我们在核心生物信息学方面努力的关键战略是升级和加强我们科学家在计算生物学和生物信息学方面的基础设施和专业知识，获得先进的计算和网络资源，并促进在健康差距研究中利用这些技术的积极研究。服务器开发：目前我们有四台服务器：三台Red Hat Enterprise Linux ES和一台Microsoft 2003服务器。校园内的计算机可以访问服务器上的软件。网站开发：我们已经开发并继续升级以下网站： A)TU的RCMI网站：http://compepid.tuskegee.edu/rcmi/RCMITu.htm. B)兽医、护理和保健学院网站http://www.onemedicine.tuskegee.edu. C)健康差距网站http://www.healthdisparity.tuskegee.edu.该网站拥有丰富的AL黑带12县健康差距数据库资源。 D)数据仓库网站http://www.onemedicinedb.tuskegee.edu.数据仓库目录帮助我们的用户浏览CVMNAH数据仓库中包含的信息。这个数据仓库的一个目标是开发和实施一个评估计划，以评估CVMNAH的生产力和问责制。数据仓库将被用作一个跟踪系统，以使CVMNAH能够回应内部和外部对问责的要求，并对学生的进步和机构成果评估的生产率进行切实的衡量。这也有一个进入CVMNAH的在线申请。 E)TU RCMI网站下的生物信息学网站上有各种不同类别的精选资源和数据，可供对生物信息学和健康差异http://compepid.tuskegee.edu/rcmi/RCMI.htm.领域感兴趣的科学家使用年度生物医学研究研讨会：作为促进共享正在进行的生物医学研究活动以及解决处理健康差距问题的战略的一部分，CCEBRA组织了十个年度生物医学研究研讨会，于每年9月的最后一周在塔斯基吉大学凯洛格会议中心举行。共享资源：CCEBRA除了为研究生提供统计支持外，还为TU的教职员工和研究人员提供统计分析服务。塔斯基吉大学的NCBI现场指南：TU的CCEBRA以前曾主持过两门课程，题为“基因库和NCBI分子生物学资源的现场指南”，我们预计当他们恢复提供时，我们将再次主持这两门课程。国家医学图书馆下属的国家生物技术信息中心(NCBI)提供了这些课程，并由NCBI的讲师授课。有关示例，请访问：http://compepid.tuskegee.edu/rgsevents/NCBI2006/NCBITu.htm.

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics. The key strategy in our endeavors in the core Bioinformatics is to upgrade and strengthen the infrastructure and expertise of our scientists in computational biology and bioinformatics, acquire advanced computational and network resources and promote active research that exploits these technologies in health disparity studies. Server Development: Currently we have four servers: Three Red Hat Enterprise Linux ES and one Microsoft 2003 server. The software on the servers is accessible to computers on the campus. Website development: We have developed and continued to upgrade the following websites: a) TU's RCMI website: http://compepid.tuskegee.edu/rcmi/RCMITu.htm. b)The College of Veterinary Medicine, Nursing and Allied Health (CVMNAH) website http://www.onemedicine.tuskegee.edu. c) The health disparities website http://www.healthdisparity.tuskegee.edu. He site has rich resources of health disparity databases for the 12 black belt counties of AL. d) The data warehouse website http://www.onemedicinedb.tuskegee.edu. The Data Warehouse Directory helps our users to navigate through the information contained in CVMNAH's Data Warehouse. One objective of this data warehouse is to develop and implement an evaluation program to assess the productivity and accountability of the CVMNAH. The data warehouse will be used as a tracking systems to enable CVMNAH respond to internal and external demands for accountability with tangible measurements of productivity both for students' progress and institutional outcomes assessment. This also has an online application for admission into the CVMNAH. e) The Bioinformatics website, under the TU's RCMI website, has a rich variety of selected resources in different categories and data which can be used by scientists interested in the area of bioinformatics and health disparities http://compepid.tuskegee.edu/rcmi/RCMI.htm. The Annual Biomedical Research Symposium: As part of the strategy to promote sharing of biomedical research activities that are in progress as well as to address national issues dealing with Health Disparities, CCEBRA organized ten annual biomedical research symposia which were held during the last week of every September at the Kellogg Conference Center, Tuskegee University. Shared Resource: CCEBRA has been providing service in statistical analysis for faculty and researchers at TU in addition to statistical support for graduate students. NCBI field guide in Tuskegee University: CCEBRA at TU previously hosted two courses entitled "A Field Guide to GenBank and NCBI Molecular Biology Resources" we anticipate to host them again when they resume offering them. The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine offered the courses and they were given by instructors from NCBI. See the sample at: http://compepid.tuskegee.edu/rgsevents/NCBI2006/NCBITu.htm.