COMPUTATIONAL BIOLOGY & BIOINFORMATICS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics. The key strategy in our endeavors in the core Bioinformatics is to upgrade the infrastructure and expertise of our scientists in computational biology and bioinformatics, acquire advanced computational and network resources and promote active research that exploits these technologies in health disparity studies. Server Development: We have migrated to a Linux server (Red Hat Enterprise Linux ES). We have moved all our data into the new server. We have also put some of the software on the server to be accessible to computers on the TU campus. Website development: A new website development has been completed and will be tested and soon be online. We have also started the base line links and data to be used for scientists interested in the area of Bioinformatics and Health disparities. Research Coordination Network (RCN): Discussed collaboration with Montgomery Aids Outreach (MAO) over some period of time and have now agreed upon a partnership with MAO with detailed protocol to collect data from the black belt counties (BBC) of Alabama. Sponsoring the sixth annual biomedical research symposium: As part of the strategy to promote sharing of biomedical research activities that are in progress as well as to address national issues dealing with Health Disparities, CCEBRA has organized the sixth annual biomedical research symposium that was held September 29-30, 2005 at the Kellogg Conference Center, Tuskegee University. Shared Resource: CCEBRA has been providing service in statistical analysis for faculties and researchers in TU. Developed sharable data sources related to the health disparities project that included HIV/AIDS, infant mortality rate, cancer, diabetes and cardiovascular diseases for the BBC in Alabama as well as other comparison counties. Created summary tables, graphs and maps using GIS tools. Made the databases available (hardcopy and electronic formats) to be shared by scientists who need information to advance biomedical research dealing with health disparities studies in Alabama with a special focus on the Black Belt and rural counties of Alabama. NCBI filed guide in Tuskegee University: The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine has led the way in establishing useful bioinformatics resources for the biomedical research community, including PubMed, GenBank, Entrez and others. In the week of August 27, 2006, our center at Tuskegee University will host a course entitled "A Field Guide to GenBank and NCBI Molecular Biology Resources". The course will be given by instructors from NCBI. Timely reminders will also be posted. The seminar is intended for Tuskegee University RCMI scientists and faculty, staff and students from other areas of the Tuskegee University campus. Certificates of Attendance from NCBI will also be given to workshop participants.