Core 3: Computational (290-307)

计算建模核心的设计是为了支持生物学上可信的 该中心提出的各种项目的计算模型。各种现有的型号都有 为在所有拟议项目中采用的实验任务而制定。这包括 认知控制模型(项目1)、学习模型(项目2)、情绪模型(项目3)、认知控制模型(项目1)、学习模型(项目2)、情绪模型(项目3) 执行职能(项目4)和儿童发展(项目5)。因为这些模型是生物学上的 受此启发，他们同时考虑了神经生物学和心理上对加工的限制。最新进展 提供了一种综合机械学实验结果的重要途径。 时尚，并为进一步的实验研究产生预测。这些模型将并行使用 进行实证性的调查，这样他们就可以相互通报。由于这些特点， 计算核心明确地解决链接分析级别的中心目标(计算， 心理学和神经生物学)在我们对执行功能的理解中。 与计算核心相关的人员将为教师和博士后提供 在为所有项目创建、实施和评估计算模型方面的专业知识 在中间。此外，它还将为这些调查提供计算基础设施。 作为中心成员的培训材料和培训机会。 执行功能的计算模型可以提供对许多精神障碍的洞察 方式。例如，可以对模型进行“损伤”或更改，而这在实验上是不可能实现的。 无论是出于道德原因还是出于实际原因。因此，它们可以提供对支持的机制的见解 混乱的思想或情绪过程。此外，它们还可以提供对机制或 可能有效克服这类障碍的干预措施。这一点对模型来说尤其正确 建议用于该中心，它们与神经解剖学和大脑系统的功能明确相关，如 以及支持执行功能的心理过程。

The computational modeling core is designed to support the development of biologically plausible computational models across the range of projects proposed in the center. Various existing models have been developed for the experimental tasks employed across all of the proposed projects. This includes models of cognitive control (Project 1), learning (Project 2), emotion (Project 3), dompainergic infulences on executive funciton (Project 4) and child development (Project 5). Because these models are biologically inspired they consider both neurobiological and psychological constraints on processing. The development of computational models provides an important way of synthesizing experimental results in a mechanistic fashion, and generating predictions for further experimental studies. These models will be used in parallel with empirical investigations so that theycan inform each other. Because of these characteristics, the computational core explicitly addresses a center goal of linking levels of analysis (computational, psychological, and neurobiological) in our understanding of executive function. The personnel associated with the computational core will provide both the faculty and post-doctoral expertise with regards to the creation, implementation and evaulation of comptuational models for all projects within the center. In addition, it will provide the computational infrastructure for those investigations as well as training materials and training opportunity for center members. Computational models of executive function can provide insights into psychiatric disorders in numerous ways. For example, models can be "lesioned" or altered in ways that are impossible to do experimentally for either ethical or practical reasons. As such, they can provide insights into the mechanisms that support disordered thoughts or emotional processes. Furthermore, they may provide insights into mechanisms or interventions that might be effective in overcoming such disorders. This is especially true of the models proposed for this center, which are explicitly linked to the neuroanatomy and functioning of brain systems as well as the psychological processes that support executive function.