Training in Cardiovascular Biology: PREDOCTORAL

描述（由申请人提供）：这是2003年启动的全校博士预科培训计划的更新申请。它旨在培养每年6名心血管生物学领域的研究生。心血管疾病是美国死亡率和发病率的主要原因，因此需要在基础研究和转化研究方面作出重大努力。该培训计划为培训未来的科学家提供了一种形式，这些科学家将投入时间和精力开发研究和控制这种疾病的工具。该申请的主要目标是为博士和医学博士提供正式的研究和学术培训。这些候选人是从医学院的申请者中精心挑选出来的，从而吸引了有能力的年轻科学家对心血管研究的关注，从而引领了生物医学研究的道路。提供与心血管疾病相关的培训，包括动脉粥样硬化、心力衰竭和高血压，并应用生理学、药理学、生物化学、分子生物学和遗传学等学科。课程还包括心血管生物学的特殊课程，同样强调跨学科和转化研究。学员参加我院惠特克心血管研究所（CVI）的各项活动。培训师资隶属于基础科学系、医学部和CVI。培训计划的成员之间有很强的研究互动，在教师和学生的水平。每个教员都有教学经验，都有几名学员继续担任学术职位，并且都至少有一项来自NIH的积极资助。在资助期间，我们能够培养在研究和学术方面取得成功的研究生。他们中的一些人在我们学校的研究生成就日获得了奖励。毕业后继续心血管生物学博士后培养。因此，该项目可能是独一无二的，因为它提供了一个机会，在一个学术环境中培养基础和转化心血管研究的博士前研究员，在这个学术环境中，可以获得大量的经验，在心血管生物学的前沿资助和跨学科研究正在进行中，并且通过学术导师的方法提供对研究生需求的敏感性。

DESCRIPTION (provided by applicant): This is a renewal application for a SCHOOL-WIDE PREDOCTORAL training program, which was initiated in 2003. It is designed to train yearly six graduate students in the field of Cardiovascular Biology. Cardiovascular diseases represent the major causes of mortality and morbidity in the United States, and thus require major efforts in fundamental and translational research. The training program provides a format for the training of future scientists who will devote time and efforts in developing the tools to study and control the disease. The major goal of this application is to provide a formal research and academic training for Ph.D. as well as M.D.-Ph.D. candidates that have been carefully selected from a total pool of applicants to the medical school, thus capturing attention of competent young scientists to cardiovascular research, leading the way to a career in biomedical research. Training is offered in topics related to cardiovascular disease, including atherosclerosis, heart failure and hypertension, with application of disciplines such as physiology, pharmacology, biochemistry, molecular biology and genetics. The curriculum also includes special courses in cardiovascular biology, with equal emphasis on interdisciplinary and translational research. Trainees participate in various activities of the Whitaker Cardiovascular Institute (CVI) at our institute. The training faculty is affiliated with basic science departments, the department of Medicine and with the CVI. There are strong research interactions between members of the training program, at faculty and student levels. Each faculty has experience in teaching, all have had several trainees that have gone on to hold academic positions, and all have at least one active grant from NIH. During the funding period we were able to train graduate students with documented success in research and academic sl<ills. Several of them were awarded on Graduate Student Achievement Day at our school. Those who graduated continue post-doctoral training in Cardiovascular Biology. Hence, the program may be unique in that it provides an opportunity to train predoctoral fellows in basic and translational cardiovascular research in an academic setting in which considerable experience is available, where cutting-edge funded, interdisciplinary research in Cardiovascular Biology is ongoing, and where sensitivity to the need of graduate students is provided by an academic mentor approach.