Nutritional Epidemiology of Cancer Education and Career Development Program

描述（由申请人提供）：这是第二次也是最后一次重新提交，以寻求为R25教育计划，癌症的营养流行病学更新资金。之前的审查总结得出结论，“这是一个非常强大和独特的计划。Stampfer博士似乎已经解决了早期申请中提出的大部分问题。这是一个杰出的计划。“最初的建议是在NCI培训分支的鼓励和建议下提交的。通过扩大教育和培训计划推进营养研究是国家癌症研究所癌症预防司的高度优先事项。该计划包括提供持续的领导力，专门的教师时间，明确的专业课程，跨学科的研究环境，以及每个学员的两个（或更多）导师。这个跨学科，但重点突出，计划是基于营养和流行病学的接口。它由Meir Stampfer博士领导，Walter Willett博士担任共同首席研究员，Edward Giovannucci博士担任教育总监，Stephanie Smith-Warner博士担任副教育总监，并增加了Lorelei Mucci博士。最终目标是训练研究人员发现饮食变化可以降低癌症风险和负担的新方法。该计划，现在在其第六年（通过无成本延长），已经建立了一个坚实的成就记录。它还利用了哈佛公共卫生学院流行病学和营养学系的其他资源，该学院长期以来一直是流行病学方法、一般癌症流行病学和营养流行病学方面公认的教学和实践培训中心。该教育计划还利用了Dana-Farber/哈佛癌症中心（DH/HCC）内的各种研究机会，该中心是一个矩阵癌症中心，代表了七个哈佛附属机构的癌症研究。R25借鉴了饮食和癌症领域的重大发展，例如创建了三个大型队列，其中包括超过25万名男性和女性，随访时间长达28年，并重复测量饮食。通过这项培训补助金，我们汇集了已经到位的各种元素，并创造了新的元素，以建立一个连贯和集中的跨学科计划，在癌症的营养流行病学。癌症营养流行病学方案提供了一个独特的利基，同时与其他培训赠款互补和协同作用，以便在健全的生物学基础上为癌症预防和控制营造一个强大的环境。这项新计划在吸引优秀候选人方面已经取得了显着的成功。完成该计划的受训人员都已开始在这一领域从事有前途的职业。

DESCRIPTION (provided by applicant): This is the second and final resubmission to seek renewal of funding for the R25 education program, Nutritional Epidemiology of Cancer. The previous review summary concluded that "This is a very strong and unique program. Dr. Stampfer appears to have addressed most of the problems raised in the earlier application. This is an outstanding program." The original proposal was submitted with the encouragement and advice of the NCI Training Branch. Advancing nutrition research through expanded education and training programs is a high priority of the Division of Cancer Prevention at the National Cancer Institute. This program includes provision of sustained leadership, dedicated faculty time, a well-defined specialized curriculum, interdisciplinary research environments, and two (or more) mentors for each trainee. This interdisciplinary, yet focused, program is based on the interface of nutrition and epidemiology. It is led by Dr. Meir Stampfer, with Dr. Walter Willett as co-Principal Investigator, Dr. Edward Giovannucci as Education Director and Dr. Stephanie Smith-Warner as Associate Education Director, and addition of Dr. Lorelei Mucci. The ultimate goal is to train researchers to discover new ways in which changes in diet can reduce the risk and burden of cancer. The program, now in its sixth year (through a no-cost extension), already has established a solid record of achievement. It has drawn on the wealth of other resources from the Departments of Epidemiology and Nutrition at the Harvard School of Public Health, which has long been a recognized center for didactic and practical training in epidemiologic methods, cancer epidemiology in general, and nutritional epidemiology. This educational program also draws on diverse research opportunities within the Dana-Farber/Harvard Cancer Center (DH/HCC), a matrix cancer center representing cancer research across seven Harvard-affiliated institutions. The R25 draws upon major developments in the area of diet and cancer such as the creation of three large cohorts comprising over 250,000 men and women followed for as long as 28 years with repeated measures of diet. Through this training grant, we have brought together the various elements already in place, and created new elements to build a coherent and focused interdisciplinary program in the nutritional epidemiology of cancer. The Nutritional Epidemiology of Cancer program provides a unique niche, while being complementary and synergistic with the other training grants in order to foster a strong environment, based on sound biology, for cancer prevention and control. This new program has already demonstrated remarkable success in attracting outstanding candidates. Trainees who have completed the program have uniformly embarked on promising careers in this area.