Bioinformatics/ Biostatics Core

生物信息学/生物统计核心(BBC核心)将使用开源的SESAME软件建立一个实验室信息管理系统，并建立一个项目数据集成网站(如http://toro.aecom.yu.edu/biodefense/).所有主要和经过处理的数据都将放在网站上。患者数据将由蒙特菲奥里医疗中心的管理信息系统保存。已经建立了防火墙，因此患者数据无法访问。只有患者和蛋白质组学的样本代码将提供给分析师。这个 生物信息学/生物统计学核心还将提供关于高级研究设计、样本规模调整和量化表达的统计分析的咨询，并使用反映个别项目的参数，并解码样本以与适当的参数相关联，如艾滋病毒、HAART、IPS、丁丙诺啡、细胞因子表达、神经症状、转移率等。

The Bioinformatics/Biostatistics Core (BBC Core) will set up a Laboratory Information Management System (LIMS) using the open source Sesame software and establish a project data integration web site (e.g.,http://toro.aecom.yu.edu/biodefense/). All primary and processed data will be placed on the web site. Patient data will be kept by MIS at Montefiore Medical Center. A firewall has been established so that patient data cannot be accessed. Only patient and sample codes for proteomics will be provided for the analysts. The Bioinformatics/Biostatistics Core will also provide consulting on advanced study design, sample size justification and statistical analysis of quantitative expression with parameters reflecting the individual projects, and decode the samples to correlate with appropriate parameters, such as ¿ HIV, ¿HAART, ¿ IPS,¿ buprenorphine, cytokine expression, neurological symptoms, transmigration rates, etc.