ENHANCEMENT OF THE HIV AND SUBSTANCE OF ABUSE LABORATORY CORE

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 加强艾滋病毒和滥用物质实验室核心将推动我们目前的努力，即提供必要的人力资源和基础设施，以支持艾滋病毒/艾滋病、滥用物质及其相关疾病领域的研究。该设施将继续支持我们和其他机构目前的研究中心。这一行政副刊将改善与社区和政府机构以及波多黎各和美国大陆其他医学院的现有合作活动。此外，它还将在顾问和导师的参与下，为试点项目提供行政和科学支助。建议的具体目标如下：1.招聘新的专门人员，在艾滋病毒和滥用物质研究应用等具有挑战性的领域引进具有竞争力的新技术。2.购置新的物资和设备，以满足日益增长的研究项目对方法的重新定位，使其更符合翻译研究的趋势。3.介绍生物标记物的发现和验证以及疫苗/免疫疗法的设计和开发。4.不仅通过招聘新人员后创造就业机会，而且通过购买新设备、用品和试剂来刺激经济。为加强目前的活动和实现拟议的具体目标，有必要提供所要求的行政补充。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The enhancement of the HIV and Substance of Abuse Laboratory Core (H-SALC) will advance our present efforts of providing human resources and infrastructure needed to support research studies in the areas of HIV/AIDS, substance of abuse and their related diseases. This facility will continue supporting current research centers in our and other institutions. This administrative supplement will improve the existing collaborative activities with community and government based agencies, and other medical schools in Puerto Rico and the mainland United States. Furthermore, it will provide administrative and scientific support to pilot projects with the participation of consultants and mentors. The following specific aims are proposed: 1. Recruit new specialized personnel to introduce new and competitive technologies in the challenging fields of HIV and substance of abuse research application. 2. Acquire new supplies and equipments to meet the increasing need of research projects for redirecting their methodology and making it more amenable to the translational research trend. 3. Introduce biomarker discovery and validation as well as vaccine/immunotherapy design and development. 4. Stimulate the economy not only by creating jobs after the recruitment of new personnel but also by purchasing new equipments, supplies, and reagents. This requested administrative supplement will be necessary to strengthen current activities and to accomplish proposed specific aims.