课题基金 / 基金详情

ULTRASTRUCTURAL INVESTIGATION OF CYTONEMES AND THEIR CONTACT POINTS

ULTRASTRUCTURAL INVESTIGATION OF CYTONEMES AND THEIR CONTACT POINTS
细胞因子及其接触点的超微结构研究
批准号：
8169645
负责人：
THOMAS B. KORNBERG
金额：
$2.39万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-04-01 至 2011-03-31
来源：
https://reporter.nih.gov/project-details/8169645
关键词：
CellsComputer Retrieval of Information on Scientific Projects DatabaseDevelopmentDrosophila genusElectron MicroscopyFundingGrantGrowth FactorGrowth Factor ReceptorsInstitutionInvestigationLarvaProcessResearchResearch PersonnelResourcesSignal TransductionSourceUnited States National Institutes of Healthimaginal disc

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 细胞丝是我们认为在发育过程中生长因子的长距离信号传导中使用的长丝状伪足过程。 细胞丝表达生长因子受体，并在接触其在成虫盘中的靶细胞之前延伸至800 μ m。 我们希望用电子显微镜研究果蝇幼虫细胞丝和靶细胞之间的接触点。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cytonemes are long filopodial processes we believe are used in long range signaling of growth factors during development. Cytonemes express growth factor receptors and extend up to 800 um before contacting their target cells in the imaginal disk. We wish to use electron microscopy to study the contact points between cytonemes and target cells in Drosophila larvae.
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