DETERMINANTS OF SELF-RENEWAL, DIFFERENTIATION, AND REPROGRAMMING OF HESCS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：由Slukvin博士领导的项目3的目标是识别对将成纤维细胞和血细胞重新编程为多能状态最关键的基因和表观遗传修饰。 该项目使用WNRPC干细胞资源。 出版物： 于静，胡凯，斯穆加奥托K，田S，斯图尔特R，斯拉克文II，汤姆森JA。无载体和转基因序列的人诱导多能干细胞。科学。2009年5月8日；324(5928)：797-801。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: The goals of project 3, led by Dr. Slukvin, are to identify genes and epigenetic modifications most critical for reprogramming fibroblasts and blood cells to pluripotent state. This project uses WNRPC Stem Cell Resources. PUBLICATION: Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin II, Thomson JA. Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences. Science. 2009 May 8;324(5928):797-801.