Depression and Anxiety Spectrum Disorders: From Basic Science to the Clinic and B

简介(申请人提供)：2011年7月，我们计划在约旦安曼举办首届中东会议，主题为“抑郁症和焦虑症谱系障碍：从基础科学到临床和回归”。孔特中心和本次会议拨款申请的首席研究员是罗切斯特大学的苏珊娜·哈伯博士。本次会议的执行委员会由下列中心成员组成：布朗大学-巴特勒医院的Ben Greenberg博士、哈佛大学-马萨诸塞州总医院的Darin Doughtery博士、哈佛大学-马萨诸塞州综合医院的Emad Eskandar博士、匹兹堡大学的Anthony Grace博士、哈佛大学-马萨诸塞州总医院的Mohamed Milad博士和波多黎各大学的Greg Quirk博士。当地组委会成员包括Munther Haddadin博士和约旦大学医学院院长Azmi Mahafzah博士。之所以选择“抑郁症和焦虑症谱系障碍”这一主题，是因为我们采访了中东的临床医生和科学家，表达了他们的兴趣和需求。执行委员会的成员由基础和临床科学家组成，代表了抑郁症和焦虑症谱系障碍的临床方面及其生理学、解剖学和药理学方面的不同专业领域。因此，拟议的会议聚集了一群独特的临床和基础科学家，他们对这些疾病这一世界性问题特别感兴趣。第一次会议的目标是将抑郁和焦虑谱系障碍的病理生理学和治疗方面的专家聚集在一个文化多样化的环境中，在文化多样化的环境中，这类疾病很普遍，但接触尖端研究的机会有限。我们将通过提供关于理解和治疗这些综合征的实验和治疗方法的数据，探索科学正在推动这一领域的新方向。最后，我们将制定该区域未来研究和培训可能性的议程，利用多名调查员的多样性和专门知识。 公共卫生相关性：抑郁症和焦虑症是一种严重的、具有共同临床特征的康复性精神健康疾病。在几个中东国家，这些疾病没有得到充分的诊断和治疗。本次会议的主题“抑郁症和焦虑症谱系障碍：从基础科学到临床和背部”和地点(约旦大学安曼，约旦)，是根据中东临床医生和科学家所表达的兴趣和需求选定的。这次由美国牵头的会议的目标是将专家带到这类疾病普遍存在的地区，但接触研究的机会有限。

DESCRIPTION (provided by applicant): In July 2011 we plan to hold our first Mideast conference on "Depression and Anxiety Spectrum disorders: from basic science to the clinic and back", in Amman, Jordan. The Principal Investigator for the Conte Center and this meeting grant application is Dr. Suzanne N. Haber, University of Rochester. The Executive Committee for this meeting consists of the following members of the Center: Dr. Ben Greenberg, Brown University-Butler Hospital; Dr. Darin Doughtery, Harvard University-Massachusetts General Hospital; Dr. Emad Eskandar Harvard University-Massachusetts General Hospital, Dr. Anthony Grace, University of Pittsburg, Dr. Mohamed Milad, Harvard University-Massachusetts General Hospital, and Dr. Greg Quirk, University of Puerto Rico. The local organizing committee includes, Drs. Munther Haddadin and Dr. Azmi Mahafzah, Dean of the Faculty of Medicine, University of Jordan. The topic, "depression and anxiety spectrum disorders", was chosen as a result of the expressed interests and needs of clinicians and scientists we spoke to in the Middle East. The members of the Executive Committee are a cross-section of basic and clinical scientists, representing different fields of expertise, in the clinical aspects of depression and anxiety spectrum disorders, and its physiology, anatomy, and pharmacology. The proposed meeting therefore brings together a unique group of clinical and basic scientists specifically interested in these diseases as a worldwide problem. The goal of this first meeting is to bring together experts on the pathophysiology and treatment of depression and anxiety spectrum disorders in a culturally diverse environment, where such disorders are prevalent, but exposure to cutting-edge research is limited. We will explore the new directions in which science is driving this field by presenting data on experimental and therapeutic approaches to understanding and treating these syndromes. Finally, we will lay out an agenda for future research and training possibilities in the region that draws upon the diversity and expertise of multiple investigators. PUBLIC HEALTH RELEVANCE: Depression and Anxiety Spectrum disorders are serious, dehabilitating mental health diseases that share common clinical features. These illnesses are under diagnosed and under treated in several Middle East countries. This topic of this meeting, "Depression and Anxiety Spectrum disorders: from basic science to the clinic and back" and venue (University of Jordan, Amman, Jordan), was chosen based on expressed interests and needs of clinicians and scientists in the Middle East. The goal of this US-led meeting is to bring experts into the region where such disorders are prevalent, but exposure to research is limited.