Persistent, Maladaptive Behaviors: Why We Make Bad Choices

项目总结/摘要 2016年10月11-13日，罗切斯特大学神经医学研究所和西尔维奥·O。孔蒂森特 将举行一次会议，题为“持续的，适应不良的行为：为什么我们做出错误的选择”。校长 调查人员是苏珊娜·N。Haber，Conte中心主任，John Foxe，罗切斯特大学研究所 神经内科主任组委会包括，本杰明格林伯格医学博士，巴特勒医院， 兰迪·巴克纳博士，哈佛大学，刘和生博士，哈佛大学，医学博士玛丽菲利普斯， 匹兹堡大学，格雷戈里·奎克博士，波多黎各大学和布朗大学医学博士Steven Rasmussen 大学当地组委会包括格雷戈里·迪安杰利斯博士，本杰明·海登博士， 布拉德马洪博士会议将包括相对较短的会谈和充分的讨论时间。 该计划旨在让基础和临床科学家参与，特别关注基础 驱动基本行为和行动计划的要素（奖励、恐惧和价值分配）;回路功能障碍 这是疾病异常的基础，具有持续的习惯性行为，尽管有些人意识到， 这些行为是适应不良的;在疾病中常见的电路组件;计算 理解这些电路的方法;以及影响这些电路的治疗方法。每个 会议开始时将进行一系列相对较短的重点会谈，然后是讨论和茶歇。 这为正式和非正式的讨论和互动提供了充足的时间。年轻科学家的海报 将在咖啡休息和用餐的同一个房间里，并在整个会议期间保持。作为 正式的演讲很短，我们将要求每位演讲者提交一篇关于他们主题的评论文章， 在我们的网站上发布会议之前。这将使与会者有机会审查背景 会议前的材料。

Project Summary / Abstract On October 11-13, 2016, the University of Rochester Institute of Neuromedicine and the Silvio O. Conte Center will hold a meeting entitled “Persistent, maladaptive behaviors: why we make bad choices”. The Principal Investigators are Suzanne N. Haber, Conte Center Director, and John Foxe, University of Rochester Institute of Neuromedicine, Director. The organizing committee includes, Benjamin Greenberg MD, Butler Hospital, Randy Buckner Ph.D., Harvard University, Hesheng Liu Ph.D., Harvard University, Mary Phillips MD, University of Pittsburgh, Gregory Quirk Ph.D., University of Puerto Rico, and Steven Rasmussen MD, Brown University. The local organizing committee includes Gregory DeAngelis, Ph.D., Benjamin Hayden, and Ph.D., Brad Mahon, Ph.D. The meeting will consist of relatively short talks and ample time for discussion. The program is designed to involve basic and clinical scientists with a specific focus on the fundamental elements that drive basic behaviors and action plans (reward, fear, and value assignment); circuit dysfunctions that underlie abnormalities in diseases with persistent, habit-like behaviors, despite some awareness that these behaviors are maladaptive; the circuit components that are common amongst diseases; computational approaches to understanding these circuits; and therapeutic approaches that effect these circuits. Each session will begin with a series of relatively short focused talks, followed by a discussion and coffee break. This gives ample time for both formal and informal discussions and interactions. Posters by young scientists will be set up in the same room as the coffee breaks and meals and will remain up throughout the meeting. As the formal presentations are short, we will ask each presenter to submit a review paper on their topic that will be posted on our web site prior to the meeting. This will give participants an opportunity to review background material before the meeting.