TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH - behavior core

CNR动物行为核心描述 D4.1。理论基础和使命。神经科学家对分子和基因技术的发展 增加了在完整和正常运作的动物体内检查体外突变的影响的必要性。功能性 对行为的分析也是研究许多神经模型的分子后果所必需的 以及与大脑中基因表达和神经化学变化相关的精神障碍 行为上的改变。然而，全面的行为表型分析通常需要专业知识和工具 超出了大多数单个实验室的财力和技术能力。因此，共享行为 设施必须是大学研究核心设施的重要组成部分。

CNR Animal Behavior Core Description D4.1. Rationale and Mission. The development of molecular and genetic technologies by neuroscientists has increased the need to examine the effects of in vitro mutations within the intact and functioning animal. Functional analysis of behavior is also required to study the molecular consequences of many modeled neurological and psychiatric disorders for which changes in gene expression and neurochemistry in the brain correlate with behavioral alterations. Comprehensive behavioral phenotyping, however, often requires expertise and instrumentation beyond the financial and technical capabilities of most individual laboratories. Thus, shared behavioral facilities need to be crucial components of university research core facilities.