International Symposium on Growth and Nutrition in Chronic Kidney Disease

描述（由申请人提供）：需要深入了解CKD中异常生长和营养的机制，这是国际儿科肾病协会（IPNA）主办的“第九届慢性肾病儿童生长和营养研讨会”的主要动机，该研讨会将于2012年4月13日至15日在美国圣地亚哥举行。其具体目标是：1）提供最新的基础、临床和转化研究信息，以及最新的营养临床实践指南 CKD的生长; 2）提供国际科学网络和合作研究的机会; 3）鼓励年轻的研究人员和学员的参与。本次会议的重点是儿童CKD的并发症，这是NIDDK的主要兴趣之一，正如纵向观察研究儿童慢性肾脏病（CKiD）的资助所证明的那样。本次会议将汇集通常不与儿科肾病学家互动的研究人员：群体遗传学家，系统生物学家，分子和神经内分泌学家，骨生物学家以及成人肾病学和工业的基础和临床研究人员。所有的参与者都应该从交流和互动中受益，否则将不会发生。CKiD研究人员还与他们的欧洲同事在4C研究中合作，进行儿童CKD进展的全基因组关联研究（由NIDDK资助），但从未进行过面对面的会议。这次会议将为来自大西洋两岸的合作者提供一个极好的机会，以建立网络并讨论目前和未来的合作。美国国立卫生研究院为这次会议提供的资金将满足专业协会或行业所不能满足的关键需求，特别是在支持年轻研究人员和受训人员参与方面。会议主题在过去一年中没有被其他会议所涵盖。本次会议为NIDDK初级研究人员提供了良好的培训环境。该计划将包括来自研究中代表性不足的群体的调查人员。青年研究人员和受训人员的参与将是本次研讨会的一个目标，并将通过制定一个杰出的科学计划来实现，这将支持他们的利益，并通过补贴他们的旅行和会议费用。科学组织委员会将选择获奖者，并为他们提供机会，在午餐期间举行的海报会议上与该领域的高级研究人员讨论他们的研究 会议的第二天。我们将特别关注妇女、少数民族、残疾人和在科学领域代表性不足的个人的参与。这些摘要将与研讨会的完整手稿沿着发表在《儿科肾病学杂志》上。 公共卫生相关性：生长不良和营养不良的身体表现与慢性肾病（CKD）儿童死亡风险增加有关。需要促进对CKD中异常生长和营养机制的深入理解，这强调了国际儿科肾病协会（IPNA）赞助的“第九届慢性肾病儿童生长和营养研讨会”将于2012年4月13日至15日在美国加利福尼亚州圣地亚哥举行的动机。

DESCRIPTION (provided by applicant): The need to foster an in-depth understanding of the mechanisms for the abnormal growth and nutrition in CKD is the main incentive for the International Pediatric Nephrology Association (IPNA)- sponsored "Ninth Symposium on Growth and Nutrition in Children with Chronic Renal Disease" to be held in San Diego, USA, April 13-15, 2012. The specific aims are to 1) provide state-of-the-art information on cutting-edge basic, clinical and translational research as well as up-to-date clinical practice guidelines in nutrition and growth in CKD; 2) provide opportunity for international scientific networking and collaborative studies; 3) stimulate the participation of young investigators and trainees. This conference focuses on the complications of CKD in children, which is one of the major interests of the NIDDK, as demonstrated by the funding of the longitudinal observation study Chronic Kidney Disease in Children (CKiD). This conference will bring together groups of investigators which do not typically interact with pediatric nephrologists: population geneticists, system biologists, molecular and neuro-endocrinologists, bone biologists as well as basic and clinical investigators in adult nephrology and industry. All participants should benefit from the cross- tal and interaction, which will not otherwise occur. CKiD investigators are also collaborating with their European colleagues in the 4C study in a genome-wide association study for progression of CKD in children (funded by NIDDK) but have never had face-to-face meetings. This conference will provide an excellent opportunity for collaborators from both sides of the Atlantic to network and discuss present and future collaborations. NIH funds for this conference will meet a critical need not met by professional societies or industry, especially when it comes to supporting the participation of young investigators and trainees. The conference topics have not been covered by other conferences in the past year. This conference provides excellent training environment for NIDDK junior investigators. The program will include investigators from groups under-represented in research. Participation of young investigators and trainees will be a goal of this symposium and will be achieved by developing an outstanding scientific program that will support their interests, and by subsidizing their travel and meeting expenses. The Scientific Organizing Committee will select the awardees and provide them the opportunity to discuss their research with senior investigators in the field during the poster session held during a lunch session on the second day of the meeting. We will give special attention to the inclusion of women, minorities, and persons with disabilities and individuals under-represented in the sciences. The abstracts will be published along with full manuscripts from the workshop, in the Pediatric Nephrology Journal. PUBLIC HEALTH RELEVANCE: Physical manifestations of poor growth and under-nutrition have been associated with increased risk of mortality in children with chronic kidney disease (CKD). The need to foster an in-depth understanding of the mechanisms for the abnormal growth and nutrition in CKD underscores the incentive for the International Pediatric Nephrology Association (IPNA)-sponsored "Ninth Symposium on Growth and Nutrition in Children with Chronic Renal Disease" to be held in San Diego, CA, USA, April 13-15, 2012.