Post Graduate Training in Pediatric Oncology

描述（由申请人提供）：科罗拉多丹佛大学（UCD）和儿童医院（TCH）的儿科血液学/肿瘤学奖学金计划拥有超过35年的杰出历史。在过去的5年里，培训计划已经受益显着过渡到新建的安舒茨医学校园（AMC）。儿科肿瘤学实验室在2004-2005学年搬迁到AMC上扩展的最先进的研究空间。2007年9月，TCH也搬迁到AMC成为一个新的144万平方英尺的医院，包括294张病床，为来自落基山脉地区七个州的病人提供服务。因此，在该计划的历史上第一次，儿科肿瘤学学员位于一个医学校园，其中包括TCH，科罗拉多大学医院，UCD医学院和科罗拉多生物科学公园。儿科肿瘤学奖学金计划和教师在向新校区过渡期间的规模也显着增长，现在由25名临床教师组成，每年有4名新研究员进入为期3年的奖学金计划。与此同时，T32研究培训学院已扩大到30名成员，增加了研究员在儿科肿瘤学中进行实验室，转化或临床研究的机会。T32培训学院代表了广泛的科学学科，包括细胞周期控制和信号传导，转录调控和剪接，病毒学和免疫学。还增加了在临床研究和转化肿瘤学方面具有特定专业知识的培训教师，包括确定药物开发的新生物靶点。培训方案最初是在2000年由T32赠款资助的，目前提交的是这一支助的第二次竞争性延期。由于临床经验的广度，儿童医院杰出的临床声誉，以及新的研究机会，自1993年以来，奖学金候选人的质量和对学术事业的奉献不断提高。事实上，在过去5年的奖学金计划的15名毕业生中，有13人现在在学术教师，自2007年以来，所有毕业生都有学术教师职位。研究金的最短期限为三年。第一年几乎完全用于临床培训，而第二年和第三年至少80%的时间用于研究。目前有12名研究员在该计划中，他们都已经完成了他们的儿科住院医师，与8目前在研究培训超过他们的第一个临床研究员年。该提案旨在为那些选择在奖学金的第二年及随后几年从事儿科肿瘤学相关研究的MD研究员提供资金，并选择致力于儿科癌症研究事业的博士博士后研究员。因此，历史和最近的发展标志着这个培训计划是全国最好的培训计划之一。

DESCRIPTION (provided by applicant): The Pediatric Hematology/Oncology Fellowship Program at the University of Colorado Denver (UCD) and The Children's Hospital (TCH) has a distinguished history spanning over 35 years. Over the last 5 years, the Training Program has benefited significantly with the transition to the newly built Anschutz Medical Campus (AMC). The Pediatric Oncology laboratories relocated in the 2004-2005 academic year into expanded, state-of-the art research space on the AMC. In September 2007, TCH also relocated onto the AMC into a new 1.44 million square feet hospital that includes 294 beds and serves patients from seven states in the Rocky Mountain region. Thus, for the first time in the history of the program, Pediatric Oncology trainees are located on one medical campus which includes TCH, University of Colorado Hospital, UCD School of Medicine, and the Colorado Biosciences Park. The Pediatric Oncology Fellowship Program and faculty also grew significantly in size during this transition to the new campus and now consist of 25 Clinical Faculty with 4 new fellows entering the 3-year Fellowship Program annually. In parallel, the T32 Research Training Faculty has been expanded to 30 members, increasing the opportunities given to fellows to perform laboratory-based, translational or clinical research in pediatric oncology. The T32 Training Faculty represent a broad range of scientific disciplines including cell cycle control and signaling, transcriptional regulation and splicing, virology, and immunology. Training Faculty with specific expertise in clinical research and translational oncology, including identification of novel biologic targets for drug development, have also been added. The Training Program was initially funded in 2000 with this T32 grant, and the current submission is the second competitive renewal of this support. Because of the breadth of the clinical experience, the outstanding clinical reputation of the Children's Hospital, and the new research opportunities available, fellowship candidates since 1993 have consistently increased in quality and dedication to an academic career. Indeed, 13 of 15 graduates in the last 5 years of the Fellowship Program are now in academic faculty, and all graduates since 2007 have academic faculty positions. The minimal fellowship duration is three years. The first year is devoted almost exclusively to clinical training, while at least 80% of time during years 2 and 3 is devoted to research. Currently there are 12 fellows in the Program, all of whom have previously completed their Pediatric residencies, with 8 currently in research training beyond their first clinical fellowship year. This proposal seeks funding for those MD fellows who elect to pursue research related to Pediatric Oncology in the second and subsequent years of the fellowship, and select PhD post-doctoral fellows committed to a career in pediatric cancer research. Both history and recent developments thus mark this training program as one of the best in the nation.