AXIS

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 描述(由申请人提供)：查尔斯·德鲁医学与科学大学(CDU)研究企业的愿景是成为全国领先的临床和转化研究资源，提供高质量、低成本和与文化相关的解决方案，改善少数族裔和贫困人口的健康和福祉。通过推动在研究团队以及研究人员和社区之间创造协同效应的战略，CDU将创建新颖的最佳实践解决方案，以改变服务不足的社区的健康，可在全国和世界范围内用作创新模式。CDU提交此申请是为了响应NIH计划公告(PAR-08-262)，以实施将健康差异综合中心(CCHD)和临床研究中心(CRC)整合为加速卓越科学(AXIS)。AXIS将成为实施CDU研究战略计划的催化剂，并将成为临床和翻译研究的一体化“家园”。Axis将拥有经验丰富和敬业的领导层；无数的临床和翻译、社区、培训和技术资源；以及出色的研究咨询服务。作为其基石，AXIS将在基民盟调查人员和社区合作伙伴之间进行多波段跨学科合作。这些团队科学活动将得到CDU生物医学信息学资源的支持，以及其他创新研究工具和信息技术(如下所述)的整合，以创建一个充满活力的临床和转化科学中心。 AXIS的总体目的是更好地定位CDU进行临床和转化性研究，特别是关注健康差异的研究。我们的目标是： 目标1：通过重组研究管理，集中和加强体力和智力资源，并促进参与RCMI翻译研究网络(RTRN)和临床和翻译科学研究所(CTSI)，将CDU研究企业从传统的基础和临床研究领域转变为高度集成的临床和翻译研究环境。 目标2：建立社区、多学科和/或多机构伙伴关系的独特模式，确保临床和转化性研究产生高质量、成本效益高的健康成果 目标3：在CDU和RTRN合作实施创新的转化性研究培训和职业发展活动，认识到基础科学、临床发现和以患者为导向的研究之间的相互依赖将加速改善患者的结果。 公共卫生相关性(由申请人提供)：未提供。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The vision of the Charles Drew University of Medicine and Science (CDU) Research Enterprise is to be a leading national resource for conducting clinical and translational research that produces high-quality, cost effective and culturally relevant solutions that improve health and wellness in minority and poor populations. By promoting strategies that create synergy in research teams and between investigators and the community, CDU will create novel best practice solutions to transform the health of underserved communities that can be used as innovative models throughout the nation and the world. CDU submits this application in response to the NIH Program Announcement (PAR-08-262) to implement the consolidation of the Comprehensive Center for Health Disparities (CCHD) and Clinical Research Center (CRC) into Accelerating Excellence in Science (AXIS). AXIS will be the catalyst to implement the CDU research strategic plan and will become the integrated "home" for clinical and translational research. AXIS will house experienced and dedicated leadership; a myriad of clinical and translational, community, training, and technology resources; and excellent research consultation services. As its cornerstone, AXIS wil have multiband interdisciplinary collaborations between CDU investigators and community partners. These team science activities will be supported by CDU biomedical informatics resources, and other innovative research tools and information technologies (detailed below) aligned in an integrated manner to create a vibrant center for clinical and translational science. The overall purpose of AXIS is to better position CDU for conducting clinical and translational research, especially research that is focused on health disparities. The goals are to: Goal 1: Transform the CDU research enterprise from traditional basic and clinical research domains into a highly integrated clinical and translational research environment by reorganizing research administration, centralizing and enhancing physical and intellectual resources, and promoting participation in the RCMI Translational Research Network (RTRN) and Clinical and Translational Science Institutes (CTSI). Goal 2: Develop a unique model for community, multi-disciplinary, and/or multi-institutional partnerships that ensures that clinical and translational research yields high-quality, cost-effective health outcomes Goal 3: Implement innovative translational research training and career development activities at CDU and in partnership with RTRN that recognize that the interdependence of basic science, clinical discovery, and patient-oriented research will accelerate improved patient outcomes. PUBLIC HEALTH RELEVANCE (provided by the applicant): Not provided.