Geriatric

City of Hope癌症和衰老研究计划的使命是与所有癌症学科的研究人员一起研究老年癌症患者面临的生物学、治疗和生存问题。这项研究的结果将适用于大多数癌症患者，因为大约60%的癌症诊断和70%的癌症死亡发生在65岁以上的患者中。老年癌症患者和癌症幸存者的数量正在迅速增长，因为美国人口正在老龄化，预计到2030年，65岁及以上的患者数量将翻一番。此外，这也显示了老年人成为照顾者的人数不断增加的趋势。虽然大多数癌症发生在老年人中，但这些患者在制定肿瘤学护理标准的国家癌症临床试验中的代表性不足。很少有研究专门关注老年人面临的独特问题，如与年龄相关的生理学下降的影响，多药治疗，或共病医疗条件对治疗耐受性的影响。 City of Hope癌症和老龄化研究计划于2006年11月制定，以解决这些老年肿瘤学研究的优先事项。在这个核心中，这些项目加入了我们癌症中心各个学科的研究人员，包括医学肿瘤学，人口科学，外科学，药理学，基础科学，护理学和生物统计学。此外，为了促进老年肿瘤学的全国性合作研究，癌症和老龄化研究计划建立了一个全国性的老年肿瘤学研究者联盟，名为“癌症和老龄化研究小组”。“这个小组的目标是加入全国各地的老年肿瘤学研究人员，共同努力设计和实施老年人临床试验，以改善老年癌症患者的护理，并促进学术老年肿瘤学家的发展，他们将继续维持老年肿瘤学领域。[6]美国

The mission of the City of Hope Cancer and Aging Research Program is to join investigators from all cancer disciplines to study the biology, treatment, and survivorship issues which face older adults with cancer. The results of this research will be applicable to the majority of patients with cancer because approximately 60% of cancer diagnoses and 70% of cancer mortality occur in patients over the age of 65. The number of older patients with cancer and cancer survivors is rapidly growing because the US population is aging with a projected doubling in the number of patients age 65 and older by 2030. Furthermore, this also presents a growing trend in the number of older adults who become caregivers. Although the majority of cancers occur in older adults, these patients have been under-represented in the national cancer clinical trials which set the standards for oncology care. Few studies have specifically focused on the unique issues which face older adults such as the impact of age related declines in physiology, polypharmacy, or impact of comorbid medical conditions on treatment tolerance. The City of Hope Cancer and Aging Research Program was developed in November 2006 in order to address these geriatric oncology research priorities. Within this Core, the projects join investigators from disciplines across our cancer center including medical oncology, population sciences, surgery, pharmacology, basic science, nursing, and biostatistics. In addition, in order to foster nationwide collaborative research in geriatric oncology, the Cancer and Aging Research Program has developed a nationwide consortium of geriatric oncology investigators, entitled the "Cancer and Aging Research Group." The goal of this group is to join geriatric oncology researchers across the nation in a collaborative effort of designing and implementing clinical trials in older adults in order to improve the care of older adults with cancer as well as to promote the development of academic geriatric oncologists who will continue to sustain the field of geriatric oncology.[6]