Lifestyle Interventions in Overweight and Obese Pregnant Women

建议进行一项随机对照试验，以研究不同种族和民族的队列中的这种影响。 对肥胖和肥胖孕妇进行强化生活方式干预(ILI)，并与 关于孕期体重增加(GWG)、婴儿肥胖和母亲产后体重的常规护理(UC) 留存。ILI手臂上的妇女将在怀孕期间接受密集咨询和团体咨询 分娩后有关行为、营养和体力活动的变化。将会出现对辅导员的访问 每周和额外的电话和互联网联系将会发生。母亲的分数将分别在14岁和36岁进行评估 孕周、产后12周和52周。测量结果将是 人体测量、全身磁共振、回声磁共振和全身体积描记(BodPod)。婴儿的 测量将包括人体测量、全身核磁共振、回声核磁共振和全身体积描记 (豆荚)用于肥胖12周和52周。母亲和孩子会有心脏代谢的危险因素 在血浆中测量。将收集有关母亲的饮食摄入量和体力活动的数据 (问卷和加速度计)，以协助咨询。其他需要收集的数据包括问卷调查 关于生活质量、社会经济地位。将仔细记录提供ILI的费用，以便 干预的成本分析可以计算出来。这项研究的主要结果是肥胖 出生时的婴儿。我们需要180名参与者才能获得适当的权力。我们将招收210人，以便允许 对一些沿途辍学的人来说。每位母亲将在怀孕期间和产后一年内接受跟踪。 送货。每个婴儿出生后将被跟踪一年。我们有能力继续遵循这些 如果有更多的资金投入，将会有更多的参与者，因为他们都是我们医院的集水区和我们的 自己的医生。如果实现了目标，即儿童和母亲都从干预中受益， 对待烤箱/蔬菜孕妇的方式应该有一个典范的转变。目前，有一种 缺乏向这些妇女提供有关GWG和体力活动的行为建议和干预。 本研究的阳性结果将为ILI的预防性干预提供证据。

A randomized controlled trial is proposed to study the effect, in a cohort of racially and ethnically diverse group of ovenweight and obese pregnant women, of an Intensive Lifestyle Intervention (ILI) compared to Usual Care (UC) on gestational weight gain (GWG), infant fatness, and mothers' post-delivery weight retention. Women in the ILI arm will receive intensive counseling during pregnancy and group counseling after delivery regarding behavior, nutrition, and physical activity change. Visits to counselors will occur weekly and additional telephone and internet contacts will occur. The mothers' will be assessed at 14 and 36 weeks of pregnancy and at 12 weeks and 52 weeks post-delivery. The measurements will be anthropometry, whole body MRI, EchoMRI, and whole body plethysmography (BodPod). The infants' measurements will be anthropometry, whole body MRI, EchoMRI, and whole body plethysmography (PeaPod) for fatness 12 weeks and 52 weeks. Mothers and children will have cardio-metabolic risk factors measured in plasma. Data will be collected regarding mothers' dietary intake and physical activity (questionnaires and accelerometry) to assist in counseling. Other data to be collected include questionnaires on quality of life, socio-economic status. Careful record will be kept of expenses in providing the ILI, so that cost analysis of the intervention can be calculated. The study is powered on the primary outcome, fatness of the infants at birth. We require 180 participants to attain appropriate power. We will enroll 210 so as to allow for some dropouts along the way. Each mother will be followed during pregnancy and for a year post delivery. Each infant will be followed for a year after birth. We have the ability to continue to follow these participants if further funding is forthcoming, as they are all local to our hospital's catchment area and our own physicians. If aims are achieved, namely that both children and mothers profit from the intervention, there should be a paradigm shift in how oven/veight pregnant women are treated. At present, there is a dearth of behavioral advice and intervention relating to GWG and physical activity provided to these women. Positive results from our studv would provide evidence for ILI preventative intervention.