Carolina Mammography Registry

描述(由申请人提供)：本提案是对国家癌症研究所RFA CA-05-502的回应，以支持基础设施的继续建设和维护，该基础设施已成为卡罗莱纳州乳房摄影登记(CMR)，作为乳腺癌监测联盟(BCSC)的一部分。BCSC是一个由七个乳房X光检查登记处组成的合作网络，与病理学和肿瘤登记处有联系。我们建议继续在北卡罗来纳州的一个地区开展CMR的工作。基于实践的前瞻性数据将直接从妇女和乳房X光检查机构的专业人员那里收集，包括：人口统计数据、乳房史数据、家族史、激素使用、筛查乳房X光检查的原因和结果、解决筛查评估所需的其他成像研究的数据以及对后续行动的建议。病理数据将前瞻性地从几个来源收集，包括直接从乳房X光检查设施收集，从快速病例报告系统收集，以及从北卡罗来纳州中央癌症登记中心下载所有乳腺癌记录的年度完整电子下载。随着知情同意的增加，以及进行特殊调查的能力，CMR将能够贡献数据，以增强研究乳腺癌的筛查、诊断、治疗和生存的能力。CMR中的数据代表了北卡罗来纳州人口的多样性和乳房X光检查设施的多样性。所有数据将与BCSC统计协调中心共享，以便由BCSC组成的登记册的调查员和外部调查员进行集中分析。将努力提高北卡罗来纳州CMR和BCSC的能见度，以便更好地将数据用于研究、规划和教育。

DESCRIPTION (provided by applicant): This proposal is in response to RFA CA-05-502 from the National cancer Institute, to support continued building and maintenance of the infrastructure that has become the Carolina Mammography Registry (CMR), as part of the Breast Cancer Surveillance Consortium (BCSC). The BCSC is a collaborative network of seven mammography registries with linkages to pathology and tumor registries. We propose to continue the work of CMR for a region of North Carolina. Prospective practice-based data will be collected directly from women and professionals in mammography facilities including: demographic data, breast history data, family history, hormone use, reason for and findings on the screening mammogram, data on other imaging studies necessary to resolve the screening assessment, and recommendations for follow-up. The pathology data will be collected prospectively from several sources including directly from mammography facilities, from a rapid case reporting system and annual complete electronic download of all breast cancer records from the NC Central Cancer Registry. With the addition of informed consent, and the ability to do special surveys, CMR will be able to contribute data to enhance the ability to study screening, diagnosis, treatment and survival for breast cancer. The data in CMR represents the diversity of the population of North Carolina and the diversity of the mammography facilities. All data will be shared with the Statistical Coordinating Center of the (BCSC) for pooled analyses by the investigators of the Registries comprising BCSC and outside investigators. Efforts will be made to increase the visibility of both CMR and the BCSC in North Carolina, to enhance use of the data for research, planning and education.