VERMONT INBRE: BIOINFORMATICS CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 生物信息学核心亮点 佛蒙特州遗传学网络生物信息学核心为佛蒙特大学，VGN学士学位合作机构和区域合作者的研究人员提供支持。在过去的一年里，我们的重点逐渐转向大型研究项目和区域合作。 明年研究工作的主要组成部分将集中在完成通过我们的联合NSF赠款（NECC）和VGN补充资助的区域项目。这些大型项目旨在开发生物信息学核心内的技术专长，实施区域合作模式，并开发和实施支持未来此类合作的基础设施。VGN生物信息学核心在区域项目中发挥主导作用。 生物信息学核心活动 研究活动（不包括微阵列） 提交的赠款 (PI或关键人员） 2 大型研究项目 7 小型研究项目 3 演讲/研讨会 4 新聘人员 2.5 基础设施和IT 学院/中心提供IT支持 13 核心设施数据库 237 科学网络创建 1 区域合作 5 微阵列设施-生物信息学支持 项目总数 45 调查人员 38 场外研究者 10 文件/介绍 1/1 项目亮点 - 建立了一个区域生物信息学核心的虚拟组织-东北生物信息学协作组织 主导开发和实施NECC共享数据中心 - 通过云计算测试模型工作流程，将资本支出转换为运营支出，以满足分析需求 - 发展并行（下一代）通过实施虚拟基因组核心设施提供测序支持 - 领导区域蓝藻宏基因组学研究的生物信息学核心 - 领导区域Little Skate基因组序列项目的生物信息学核心 基础设施发展 - Little Skate Annotation Jamboree组委会成员 - NECC区域光纤网络项目技术委员会成员 - 开发和维护国家IDEA资助的核心实验室（NICL）的网站 - ABRF网络委员会成员 - 维持区域核心设施数据库 - 领导NERLSCD区域核心设施会议的IT

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Bioinformatics Core Highlights The Vermont Genetics Network Bioinformatics Core provides support to researchers at the University of Vermont, VGN Baccalaureate Partner Institutions and regional collaborators. In the past year our focus has gradually shifted toward large research projects and regional collaborations. The major component of research work over the next year will be focused on completion of regional projects funded through our joint NSF grant (NECC) and the VGN supplement. These large scale projects were designed to develop technical expertise within the Bioinformatics Core, to implement a model for regional collaborations and to develop and implement the infrastructure to support such collaborations in the future. The VGN Bioinformatics Core plays a lead role in the regional projects. Bioinformatics Core Activities Research Activities (Excluding Microarray) Grants Submitted (PI or Key Personnel) 2 Large Research Projects 7 Small Research Projects 3 Presentations/Seminars Given 4 New Personnel Hired 2.5 Infrastructure and IT Colleges/Centers Provided IT Support 13 Core Facility Database Entries 237 Science Networks Created 1 Regional Collaborations 5 Microarray Facility - Bioinformatics Support Total Projects 45 Investigators 38 Off-Site Investigators 10 Papers / Presentations 1/1 Project Highlights -established a virtual organization of regional bioinformatics cores - North East Bioinformatics Collaborative -led development and implementation of a shared data center for NECC -tested model workflows with cloud computing to convert capital expenses to operational expenses for analysis needs -developing parallel (next gen.) sequencing support through implementation of a virtual genomics core facility -Lead Bioinformatics Core for regional cyanobacteria metagenomics study -Lead Bioinformatics Core for regional Little Skate genome sequence project Infrastructure Development -Member organizing committee for Little Skate Annotation Jamboree -Member technical committee for NECC regional fiber network project -developed and maintain the website for the National IDeA Funded Core Laboratories (NICL) -Member ABRF web committee -maintain a Regional Core Facilities database -Lead IT for NERLSCD regional core facilities meeting