NANOSTRUCTURED CARBON NANOTUBE/HYDROXYAPATITE AND CARBON NANOTUBE/TITANIA (TIO2)

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 电沉积纳米碳纳米管/羟基磷灰石和碳纳米管/二氧化钛(TiO2)复合膜 多年来，人们一直使用金属植入物来修复和替代骨骼。最近，研究的目标是通过使用物理和化学方法来改善种植体的固定。羟基磷灰石(HAP)作为钛种植体表面沉积的一层薄层，与人类骨骼相似，具有良好的生物相容性。然而，目前HAP涂层是通过高温等离子喷涂技术沉积的，这导致了由不确定的相(化学成分未知)和不希望的厚膜(导致微裂纹)组成的不可预测的薄膜。 我们建议使用溶液相电泳沉积(EPD)技术在钛金属衬底上制备高质量和可重复的涂层。涂层将由纳米羟基磷灰石(HAP)、金红石和锐钛矿型二氧化钛以及碳纳米管(CNT)组成。纳米粒子将使用粒度分析、Zeta电位法、BET比表面积和光谱技术进行表征。所制备的复合涂层由羟基磷灰石/碳纳米管、金红石/碳纳米管、锐钛矿型/碳纳米管和羟基磷灰石/二氧化钛/碳纳米管组成。这些涂层将用拉曼光谱、FT-IR、X射线衍射和扫描电子显微镜(SEM)进行检测。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Nanostructured Carbon Nanotube / Hydroxyapatite and Carbon Nanotube / Titania (TiO2) Composite Films by Electrophoretic Deposition (EPD) Metallic implants have been used for many years to repair and replace bone. More recently, studies have been directed at improving implant fixation by using physical as well as chemical methods. Calcium hydroxy phosphate (better known as hydroxyapatite, or HAP), as a deposited thin layer on titanium implants, exhibits excellent biocompatibility because of its similarity to human bone. However, HAP coatings are currently deposited by high-temperature plasma spraying techniques that result in unpredictable films consisting of undefined phases (chemical composition unknown) and undesirable thick films (causing micro-cracking). We propose using the solution-phase technique of electrophoretic deposition (EPD) to produce high-quality and reproducible coatings on titanium metal substrates. The coatings will consist of nanoparticles of hydroxyapatite (HAP), rutile and anatase forms of TiO2, and carbon nanotubes (CNT). The nanoparticles will be characterized using particle-size analysis, zeta potentiometry, BET surface-area, and spectroscopic techniques. The composite coatings that will be produced consist of HAP/CNT, rutile/CNT, anatase/CNT, and HAP/TiO2/CNT. These coatings will be examined using Raman spectroscopy, FT-IR, X-ray diffraction, and scanning electron microscopy (SEM).